- Title
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Elevated EGFL6 modulates cell metastasis and growth via AKT pathway in nasopharyngeal carcinoma
- Authors
- Zhu, Z., Ni, H., You, B., Shi, S., Shan, Y., Bao, L., Duan, B., You, Y.
- Source
- Full text @ Cancer Med
EGFL6 gain of function increased the migration of NPC cells in zebrafish. We selected embryos at 24 h for green hearts, and observed the red fluorescence in embryos after heat?shocked for 1 h. A, hsp70l:EGFL6?mcherry embryos at 48 hpf (hours post fertilization), after heat?shocked for 1 h at 24 hpf. B, hsp70l:EGFL6?mcherry :: fli1ep: CAAX?EGFP transgenic line embryos at 48 hours, after heat?shocked for 1 h at 24 hpf. C and D, CNE2 cells labeled with dil were injected into hsp70l:EGFL6?mcherry :: fli1ep: CAAX?EGFP transgenic line embryos at 48 hpf. Then, the migration of CNE2 cells was detected at 2 d post injection. Dpf (days post fertilization). Arrows indicate tumor foci. ** P <0.01 |