- Title
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Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer
- Authors
- Schneider, J.A., Craven, T.W., Kasper, A.C., Yun, C., Haugbro, M., Briggs, E.M., Svetlov, V., Nudler, E., Knaut, H., Bonneau, R., Garabedian, M.J., Kirshenbaum, K., Logan, S.K.
- Source
- Full text @ Nat. Commun.
Zebrafish phenotypic assay of Wnt signaling. a Schematic for experimental design. b?d Images of 24?h post-fertilization of zebrafish embryos treated with vehicle alone (b), vehicle plus BIO to activate Wnt signaling (c), or macrocycle 13 in combination with BIO (d). Red arrows point to developing eye structures. Scale bar represents 500??m |
Zebrafish experiment replicates. (a) Zebrafish treated with 10 ?M Linear 13 and 2?M BIO corresponding to Fig. 6. (b) Replicates for zebrafish experiments. Red arrows point to developing eye structures. Scale bars represent 500 ?m. |