FIGURE SUMMARY
- Title
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Transient acceleration of autophagic degradation by pharmacological Nrf2 activation is important for retinal pigment epithelium cell survival
- Authors
- Saito, Y., Kuse, Y., Inoue, Y., Nakamura, S., Hara, H., Shimazawa, M.
- Source
- Full text @ Redox Biol.
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RS9 also protected adult zebrafish retina from intense light exposure via the autophagic pathway. (A-C) Hoechst33342 staining of a cryosection of zebrafish retinas injected intravitreally with RS9 and CQ. (A) Representative image (Hoechst33342: cyan). Scale bar = 10 µm. (B) ONL thickness. (C) ONL cell number. Mean ± SEM (n = 5–6). vs. control **P < 0.01, vs. vehicle; ‡P < 0.01, vs. RS9; $$P < 0.01. ONL: outer nuclear layer, INL: inner nuclear layer, GCL: ganglion cell layer. PHENOTYPE:
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Full text @ Redox Biol.