Neither histopathological changes (a–c) nor differences in the motor function outcome in the open field paradigm (d–f) were found after a single dose of CBDP or DFP. (a–c) Representative sections of the caudal spinal cord sections of adult zebrafish from the control (a,a’), CBDP (b,b’) and DFP (c,c’) groups, 3 weeks after injection. Sections were stained with Luxols Fast Blue (a–c) and Hematoxylin & Eosine (a’–c’); (D) The OFT setup allowed us to simultaneously analyze four adult fish, video-recording and tracking the movement of the fish for 6 min. (e,f) No significant differences between the total distance traveled by the control and the CBDP (b) and DFP (c) groups were found at any time. Data from 2–3 independent experiments are shown.