FIGURE SUMMARY
- Title
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Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling
- Authors
- Zhou, X., Yue, G.G., Liu, M., Zuo, Z., Lee, J.K., Li, M., Tsui, S.K., Fung, K.P., Sun, H., Pu, J., Lau, C.B.
- Source
- Full text @ Oncotarget
The inhibitory effects of EriB on the formation of subintestinal vessel (SIV) of Tg(fli1:EGFP) zebrafish embryos. A. Chemical structure of EriB. B. The SIVs of zebrafish embryos treated with vehicle control (0.1% DMSO) developed into a smooth basket-like structure. Embryos treated with EriB (5, 10, 15 μM) for 72 h leads to an inhibition of SIV formation (magnification, ×100). C. The average length of SIVs was measured as described in materials and methods in total 80 zebrafish embryos. Each values was presented as means + SEM (n=80), **p < 0.01, ***p < 0.001 compared with control group (one-way ANOVA). |
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Full text @ Oncotarget