FIGURE SUMMARY
Title

The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization

Authors
Treat, A.C., Wheeler, D.S., Stolz, D.B., Tsang, M., Friedman, P.A., Romero, G.
Source
Full text @ PLoS One
Fig. 1

NHERF1-/- depletion causes hydrocephalus.

(A), Comparison of two 28-day old NHERF1+/+ (left) and NHERF1-/- (right) littermates. (B) Nissl-stained coronal sections from NHERF1+/+ (left) and NHERF1-/- mice at P28. (C) Depletion of nherf1 in zebrafish embryos caused hydrocephalus (arrows) 2 days post-fertilization.

PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec
Fig. 2

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Fig. S1

A: D. rerio embryos injected with Splice-MO develop hydrocephalus (48 h post- fertilization). B: Posterior crista of the otic vesicle of a D.rerio embryo injected with Splice-MO. Ac-tubulin: acetylated tubulin. The phalloidin stain highlights the apical localization of actin.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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