- Title
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"Young at heart": Regenerative potential linked to immature cardiac phenotypes
- Authors
- Gomes, R.S., Skroblin, P., Munster, A.B., Tomlins, H., Langley, S.R., Zampetaki, A., Yin, X., Wardle, F., Mayr, M.
- Source
- Full text @ J. Mol. Cell. Cardiol.
DIGE comparison of the cardiac proteome. A) Overlay of adult zebrafish (red) and adult mouse (green) where overlapping proteins are seen by yellow colour. Note that there are few common protein spots between the adult mouse and adult zebrafish heart. B) Adult mouse (red) and neonatal mouse (day 0, green) heart protein overlay where overlapping proteins are again yellow. C) Principle component analysis. Analysis of differential protein expression on neonatal (day 0, red), day 4 (pink), day 14 (2 weeks, green) and adult mouse hearts (blue). The protein expression among the groups is clearly differentiated. |
DIGE Analysis. A) Differentially expressed proteins between the adult mouse heart versus zebrafish (ZF) heart (Supplementary Tables 2 and 3, respectively). B) Differentially expressed proteins between the neonatal and adult mouse heart. Note that in panel B results of Fig. 1B were reproduced with different biological replicates using a dye swap. The numbered spots were analysed by LC-MS/MS. |
Reprinted from Journal of Molecular and Cellular Cardiology, 92, Gomes, R.S., Skroblin, P., Munster, A.B., Tomlins, H., Langley, S.R., Zampetaki, A., Yin, X., Wardle, F., Mayr, M., "Young at heart": Regenerative potential linked to immature cardiac phenotypes, 105-8, Copyright (2016) with permission from Elsevier. Full text @ J. Mol. Cell. Cardiol.