FIGURE SUMMARY
Title

Custos controls β-catenin to regulate head development during vertebrate embryogenesis

Authors
Komiya, Y., Mandrekar, N., Sato, A., Dawid, I.B., Habas, R.
Source
Full text @ Proc. Natl. Acad. Sci. USA
Fig. 5

Custos is required for anterior development in zebrafish. (A and B) 25-100 pg of Myc-tagged Custos RNA was injected into the one-cell embryo and scored at 28 h postfertilization (hpf) for suppression of head development by the V1-V4 index. The numbers above each bar indicate the number of injected embryos. (C and E) Injection of Custos MO1 (C) or Custos MO2 (E) suppressed head and eye development which was rescued by coinjection of Custos Rescue RNA (2-4 pg). MOs (5-15 ng) were injected at the one-cell stage and embryos were scored at 24 hpf. (D and F) Quantitation of the results in C and E, respectively. The numbers above each bar indicate the number of injected embryos.

PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA
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