FIGURE SUMMARY
Title

Alzheimer's-Related Peptide Amyloid-beta Plays a Conserved Role in Angiogenesis

Authors
Cameron, D.J., Galvin, C., Alkam, T., Sidhu, H., Ellison, J., Luna, S., and Ethell, D.W.
Source
Full text @ PLoS One

Morphology and vascular imaging of GFP-expressing zebrafish embryos.

A) Projection image of a 3 dpf embryo using images captured by confocal microscopy. B, C) Comparable projection of a 3 dpf embryo treated with Aβ (25 μg/mL) and Rev Aβ, respectively. Boxes indicate the region analyzed for CtA branching, shown in detail in figure 4. Scale bar = 100 μm, for A–C.

EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Protruding-mouth

Comparison of cerebrovascular structures in control zebrafish embryos at 3–7 dpf. Embryos expressed GFP in endothelial cells and images were captured with a confocal microscope.

EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage Range: Protruding-mouth to Days 7-13

Gamma-secretase inhibitor effects on morphology. A) Dorsal view of 4 dpf embryos: control – top, Aβ [25] treated – middle, and GSI treated – bottom. B, C) Lateral view of control and GSI- treated 4 dpf embryos, respectively.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One