- Title
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Analysis of MicroRNA Expression in Embryonic Developmental Toxicity Induced by MC-RR
- Authors
- Zhao, Y., Xiong, Q., and Xie, P.
- Source
- Full text @ PLoS One
The survival, malformation rates and different developmental defects of zebrafish embryos induced by MC-RR. (A) The survival rates of embryos after MC-RR exposure at 24, 48 and 72 hpf, respectively. (B) The malformation rates of embryos after MC-RR treatment at 72 hpf. Various morphological deformities were detected in MC-RR-treated embryos, including bent tail/body axes (D, E, F), cyclopia (G), as well as edema in pericardial sac (PS) and hatching gland (HG) (H), compared to control embryos (C). Values are expressed as mean ± SD (*indicates significant change compared to control at p<0.05, **indicates significant change compared to control at p<0.01). PHENOTYPE:
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MC-RR exposure decreased the number of complete ISVs. Treated with MC-RR resulted in a significant reduction in the number of complete ISVs at 48 hpf (A and B) and 72 hpf (A and C), respectively, compared with controls. Arrowheads indicate complete ISVs. Asterisks indicate incomplete ISVs. (**indicates significant change compared to control at p<0.01). EXPRESSION / LABELING:
PHENOTYPE:
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