FIGURE SUMMARY
- Title
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Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis
- Authors
- Sinha Roy, R., Soni, S., Harfouche, R., Vasudevan, P.R., Holmes, O., de Jonge, H., Rowe, A., Paraskar, A., Hentschel, D.M., Chirgadze, D., Blundell, T.L., Gherardi, E., Mashelkar, R.A., and Sengupta, S.
- Source
- Full text @ Proc. Natl. Acad. Sci. USA
Effect of 1K1 and 1K1-NP mediated angiogenesis in vivo using zebrafish model. 1K1 or 1K1-NP were injected with growth-factor-reduced matrigel (Mgel) near the subintestinal vessel. SIVs were then stained with alkaline phosphate and visualized in bright field. (A): vehicle (Mgel); (B) empty PLGA in Mgel (C) 1K1 in Mgel, (D) 1K1-NP in Mgel and (E) 1K1-NP. (F) Graph shows morphometric quantification of the effect of treatment on angiogenesis. Data shown mean SEM ± from n=3. |
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Full text @ Proc. Natl. Acad. Sci. USA