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ZFIN ID:
ZDB-PERS-160504-2
Oppel, Felix
Email:
Felix_Oppel@DFCI.HARVARD.EDU
URL:
Affiliation:
A. Thomas Look Lab
Address:
Department of Pediatric Oncology Dana-Farber Cancer Institute Harvard Medical School Mayer Building 630 450 Brookline Ave Boston, MA 02215 USA
Country:
United States
Phone:
Fax:
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Oppel, F., Shao, S., Gendreizig, S., Zimmerman, M.W., Schürmann, M., Viyof Ful, F., Goon, P., Chi, S.N., Aster, J.C., Sudhoff, H., Look, A.T. (2022) p53 pathway inactivation drives SMARCB1-deficient p53-wildtype epithelioid sarcoma onset indicating therapeutic vulnerability through MDM2 inhibition. Molecular cancer therapeutics. 21(11):1689-1700
Oppel, F., Ki, D.H., Zimmermann, M.W., Ross, K.N., Tao, T., Shi, H., He, S., Aster, J.C., Look, A.T. (2020)
suz12
inactivation in
p53
and
nf1
deficient zebrafish accelerates the onset of MPNSTs and expands the spectrum of tumor types to include adenocarcinoma, leukemia, and soft tissue sarcoma. Disease models & mechanisms. 13(8):
Ki, D.H., Oppel, F., Durbin, A.D., Look, A.T. (2019) Mechanisms underlying synergy between DNA topoisomerase I-targeted drugs and mTOR kinase inhibitors in NF1-associated malignant peripheral nerve sheath tumors. Oncogene. 38(39):6585-6598
Oppel, F., Tao, T., Shi, H., Ross, K.N., Zimmerman, M.W., He, S., Tong, G., Aster, J.C., Look, A.T. (2019) Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies. PLoS Genetics. 15:e1008039
NON-ZEBRAFISH PUBLICATIONS
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