ZFIN ID: ZDB-PERS-070529-3
Juárez-Morales, Jose-Luis
Email: jljuarez@cibnor.mx
URL: https://www.cibnor.gob.mx/investigacion/acuicultura/personal-investigacion-adscrito-pa
Affiliation: Lewis Lab - Syracuse
Address: Instituto Politécnico Nacional s/n, Playa Palo de Santa Rita Sur, 23096 La Paz, B.C.S. Mexico
Country: Mexico
Phone: 011 (52) 612 122 6881
ORCID ID: 0000-0001-6356-3415

My main research interest focuses on studying gene regulation during development, understanding how the genetic program regulates the specification and functions of different organ systems, and how the molecular phenotypes connect with the cell's physiological function. My area of expertise is in developmental biology; however, I use techniques applied in other fields such as genetics, molecular biology, genomics, comparative genomics, bioinformatics, cell biology, confocal microscopy, microbiology, and aquaculture. I have vast experience working with the zebrafish (Danio rerio) and the African clawed frog (Xenopus laevis) models to study development, neurodevelopment and transgenesis systems (see Juarez-Morales et al., 2017). My current work focuses on identifying genes that participate in the immune and metabolic response in commercial fish after pathogen infection, employing RNAseq and genomic and molecular analyses (see Velázquez-Lizárraga et al., 2019).

Juárez-Morales, J.L., Weierud, F., England, S.J., Demby, C., Santos, N., Grieb, G., Mazan, S., Lewis, K.E. (2021) Evolution of lbx spinal cord expression and function. Evolution & development. 23(5):404-422
Juárez-Morales, J.L., Martinez-De Luna, R.I., Zuber, M.E., Roberts, A., Lewis, K.E. (2017) Zebrafish transgenic constructs label specific neurons in Xenopus laevis spinal cord and identify frog V0v spinal neurons. Developmental Neurobiology. 77(8):1007-1020
Hilinski, W.C., Bostrom, J.R., England, S.J., Juárez-Morales, J.L., de Jager, S., Armant, O., Legradi, J., Strähle, U., Link, B.A., Lewis, K.E. (2016) Lmx1b is required for the glutamatergic fates of a subset of spinal cord neurons. Neural Development. 11:16
Juárez-Morales, J.L., Schulte, C.J., Pezoa, S.A., Vallejo, G.K., Hilinski, W.C., England, S.J., de Jager, S., Lewis, K.E. (2016) Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Development. 11:5
Schulte, C.J., Allen, C., England, S.J., Juárez-Morales, J.L., and Lewis, K.E. (2011) Evx1 is required for joint formation in zebrafish fin dermoskeleton. Developmental dynamics : an official publication of the American Association of Anatomists. 240(5):1240-1248
Wotton, K.R., Weierud, F.K., Juárez-Morales, J.L., Alvares, L.E., Dietrich, S., and Lewis, K.E. (2009) Conservation of gene linkage in dispersed vertebrate NK homeobox clusters. Development genes and evolution. 219(9-10):481-496

Velázquez-Lizárraga AE, Juárez-Morales JL, Racotta IS, Villarreal-Colmenares H, Valdes-Lopez O, Luna-González A, Rodríguez-Jaramillo C, Estrada N, Ascencio F. Transcriptomic analysis of Pacific white shrimp (Litopenaeus vannamei, Boone 1931) in response to acute hepatopancreatic necrosis disease caused by Vibrio parahaemolyticus. PLoS One. 2019 Aug 13;14(8):e0220993. doi: 10.1371/journal.pone.0220993. PMID: 31408485; PMCID: PMC6692014.