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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-060712-13
Keefe, Matthew
Email: mkeefe@enders.tch.harvard.edu
URL:
Affiliation: The Zon Lab
Address: Howard Hughes Medical Institute Children's Hospital Boston Division of Hematology/Oncology 300 Longwood Avenue, Karp 8 Boston, MA 02115 USA
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BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Strachan, L.R., Stevenson, T.J., Freshner, B., Keefe, M.D., Miranda Bowles, D., Bonkowsky, J.L. (2017) A zebrafish model of X-linked adrenoleukodystrophy recapitulates key disease features and demonstrates a developmental requirement for abcd1 in oligodendrocyte patterning and myelination. Human molecular genetics. 26:3600-3614
Keefe, M.D., Bonkowsky, J.L. (2017) Transvection Arising from Transgene Interactions in Zebrafish. Zebrafish. 14(1):8-9
Son, J.H., Keefe, M.D., Stevenson, T.J., Barrios, J.P., Anjewierden, S., Newton, J.B., Douglass, A.D., Bonkowsky, J.L. (2016) Transgenic FingRs for Live Mapping of Synaptic Dynamics in Genetically-Defined Neurons. Scientific Reports. 6:18734
Burns, C.E., Galloway, J.L., Smith, A.C., Keefe, M.D., Cashman, T.J., Paik, E.J., Mayhall, E.A., Amsterdam, A.H., and Zon, L.I. (2009) A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 113(23):5776-5782
Langenau, D.M., Keefe, M.D., Storer, N.Y., Jette, C.A., Smith, A.C., Ceol, C.J., Bourque, C., Look, A.T., and Zon, L.I. (2008) Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 27(30):4242-4248
Saltis, M., Criscitiello, M.F., Ohta, Y., Keefe, M., Trede, N.S., Goitsuka, R., and Flajnik, M.F. (2008) Evolutionarily conserved and divergent regions of the Autoimmune Regulator (Aire) gene: a comparative analysis. Immunogenetics. 60(2):105-114
Langenau, D.M., Keefe, M.D., Storer, N.Y., Guyon, J.R., Kutok, J.L., Le, X., Goessling, W., Neuberg, D.S., Kunkel, L.M., and Zon, L.I. (2007) Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21(11):1382-1395
Le, X., Langenau, D.M., Keefe, M.D., Kutok, J.L., Neuberg, D.S., and Zon, L.I. (2007) Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104(22):9410-9415
Trede, N.S., Medenbach, J., Damianov, A., Hung, L.H., Weber, G.J., Paw, B.H., Zhou, Y., Hersey, C., Zapata, A., Keefe, M., Barut, B.A., Stuart, A.B., Katz, T., Amemiya, C.T., Zon, L.I., and Bindereif, A. (2007) Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America. 104(16):6608-6613

NON-ZEBRAFISH PUBLICATIONS