ZFIN Lab: McMahon Lab

ZFIN ID: ZDB-LAB-970410-1

McMahon Lab

PI/Director:	McMahon, Andrew
Contact Person:	McMahon, Andrew
Email:	amcmahon@mcb.harvard.edu
URL:
Address:	Department of Molecular and Cellular Biology Harvard University 16 Divinity Avenue Cambridge, MA 02138 USA
Country:	United States
Phone:	(617) 496-3757
Fax:	(617) 496-3763
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

***not currently involved in zebrafish research***

Research Interests: embryonic patterning by frizzleds, frzbs, and wnts.

LAB MEMBERS

Jeong, Juhee Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Askary, A., Mork, L., Paul, S., He, X., Izuhara, A.K., Gopalakrishnan, S., Ichida, J.K., McMahon, A.P., Dabizljevic, S., Dale, R., Mariani, F.V., Crump, J.G. (2015) Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Developmental Cell. 35:358-65

Junker, J.P., Noël, E.S., Guryev, V., Peterson, K.A., Shah, G., Huisken, J., McMahon, A.P., Berezikov, E., Bakkers, J., van Oudenaarden, A. (2014) Genome-wide RNA Tomography in the Zebrafish Embryo. Cell. 159:662-75

Mao, J., McGlinn, E., Huang, P., Tabin, C.J., and McMahon, A.P. (2009) Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Developmental Cell. 16(4):600-606

Wingert, R.A., Selleck, R., Yu, J., Song, H.D., Chen, Z., Song, A., Zhou, Y., Thisse, B., Thisse, C., McMahon, A.P., and Davidson, A.J. (2007) The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros. PLoS Genetics. 3(10):1922-1938

Ingham, P.W., and McMahon, A.P. (2001) Hedgehog signaling in animal development: paradigms and principles. Genes & Development. 15(23):3059-3087

Hammerschmidt, M. and McMahon, A.P. (1998) The effect of pertussis toxin on zebrafish development: a possible role for inhibitory G-proteins in hedgehog signaling. Developmental Biology. 194:166-171

Rauch, G.-J., Hammerschmidt, M., Blader, P., Schauerte, H.E., Strähle, U., Ingham, P.W., McMahon, A.P. and Haffter, P. (1997) WNT5 is required for tail formation in the zebrafish embryo. Cold Spring Harbor symposia on quantitative biology. 62:227-233

Holder, N. and McMahon, A. (1996) Genes from zebrafish screens. Nature. 384(6609):515-516

Hammerschmidt, M., Serbedzija, G.N., and McMahon, A.P. (1996) Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes & Development. 10(19):2452-2461

Hammerschmidt, M., Bitgood, M.J., and McMahon, A.P. (1996) Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes & Development. 10:647-658