ZFIN ID: ZDB-LAB-190725-1
de Witte Lab
PI/Director: de Witte, Peter
Contact Person: de Witte, Peter
Email: peter.dewitte@kuleuven.be
URL: http://gbiomed.kuleuven.be/english/research/50000715/52455311/
Address: Laboratory for Molecular Biodiscovery KU Leuven, Gasthuisberg O&N 2 Herestraat 49, box 824 3000 Leuven
Country: Belgium
Phone: +32 16 32 34 32
Line Designation: lv

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Partoens, M., De Meulemeester, A.S., Giong, H.K., Pham, D.H., Lee, J.S., de Witte, P.A., Siekierska, A. (2021) Modelling neurodevelopmental disorders and epilepsy caused by loss of function of kif2a in zebrafish. eNeuro. 8(5):
Guarin, M., Faelens, R., Giusti, A., De Croze, N., Léonard, M., Cabooter, D., Annaert, P., de Witte, P., Ny, A. (2021) Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration. Scientific Reports. 11:12229
Van Dycke, J., Cuvry, A., Knickmann, J., Ny, A., Rakers, S., Taube, S., de Witte, P., Neyts, J., Rocha-Pereira, J. (2021) Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small-molecule inhibitors. Nature Protocols. 16(4):1830-1849
Wang, X., Giusti, A., Ny, A., de Witte, P.A. (2020) Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid. toxins. 12(4):
Li, J., Copmans, D., Partoens, M., Hunyadi, B., Luyten, W., de Witte, P. (2020) Zebrafish-Based Screening of Antiseizure Plants Used in Traditional Chinese Medicine: Magnolia officinalis Extract and Its Constituents Magnolol and Honokiol Exhibit Potent Anticonvulsant Activity in a Therapy-Resistant Epilepsy Model. ACS Chemical Neuroscience. 11(5):730-742
Hotterbeekx, A., Raimon, S., Abd-Elfarag, G., Y Carter, J., Sebit, W., Suliman, A., Nelson Siewe Fodjo, J., De Witte, P., Yibi Logora, M., Colebunders, R., Kumar-Singh, S. (2019) Onchocerca volvulus is not detected in the cerebrospinal fluid of persons with onchocerciasis-associated epilepsy. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 91:119-123
Copmans, D., Kildgaard, S., Rasmussen, S.A., Ślęzak, M., Dirkx, N., Partoens, M., Esguerra, C.V., Crawford, A.D., Larsen, T.O., de Witte, P.A.M. (2019) Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B. Marine drugs. 17(11):
Van Dycke, J., Ny, A., Conceição-Neto, N., Maes, J., Hosmillo, M., Cuvry, A., Goodfellow, I., Nogueira, T.C., Verbeken, E., Matthijnssens, J., de Witte, P., Neyts, J., Rocha-Pereira, J. (2019) A robust human norovirus replication model in zebrafish larvae. PLoS pathogens. 15:e1008009
Giusti, A., Nguyen, X.B., Kislyuk, S., Mignot, M., Ranieri, C., Nicolaï, J., Oorts, M., Wu, X., Annaert, P., De Croze, N., Léonard, M., Ny, A., Cabooter, D., de Witte, P. (2019) Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos. International Journal of Molecular Sciences. 20(7):
Siekierska, A., Stamberger, H., Deconinck, T., Oprescu, S.N., Partoens, M., Zhang, Y., Sourbron, J., Adriaenssens, E., Mullen, P., Wiencek, P., Hardies, K., Lee, J.S., Giong, H.K., Distelmaier, F., Elpeleg, O., Helbig, K.L., Hersh, J., Isikay, S., Jordan, E., Karaca, E., Kecskes, A., Lupski, J.R., Kovacs-Nagy, R., May, P., Narayanan, V., Pendziwiat, M., Ramsey, K., Rangasamy, S., Shinde, D.N., Spiegel, R., Timmerman, V., von Spiczak, S., Helbig, I., C4RCD Research Group, AR working group of the EuroEPINOMICS RES Consortium, Weckhuysen, S., Francklyn, C., Antonellis, A., de Witte, P., De Jonghe, P. (2019) Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish. Nature communications. 10:708
Swaminathan, A., Hassan-Abdi, R., Renault, S., Siekierska, A., Riché, R., Liao, M., de Witte, P.A.M., Yanicostas, C., Soussi-Yanicostas, N., Drapeau, P., Samarut, É. (2018) Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development. Current biology : CB. 28(12):1924-1937.e5