ZFIN ID: ZDB-LAB-160503-1
Liu Dong Lab
PI/Director: Liu, Dong
Contact Person: Liu, Dong
Email: liudongtom@gmail.com
URL: http://nrl.ntu.edu.cn/sjkxx/xsdw/content/7dd91afc-a1c6-47e9-b546-7e77b36d86bf.html
Address: Jiangsu Key Laboratory of Neuroregeneration, Nantong University Room 208, Building 8 19# Qixiu Road, Nantong, Jiangsu Province, China 226001
Country: China
Phone: +86-513-85051593
Fax: +86-513-85511585
Line Designation: ntu


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 9 genomic features


STATEMENT OF RESEARCH INTERESTS
To identify novel regulators of angiogenesis during embryonic development and tissue regeneration.


LAB MEMBERS
Gao, Yu Graduate Student Qi, Jialing Graduate Student Qin, Yinyin Graduate Student
Yin, Zhenhua Graduate Student Yuan, Wei Graduate Student Gong, Jie Research Staff
Shi, Yunwei Research Staff Wang, Xin Research Staff Yang, Jinxian Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Sheng, J., Jiang, B., Shi, R., Shi, L., Liu, D. (2022) Sema4C Is Required for Vascular and Primary Motor Neuronal Patterning in Zebrafish. Cells. 11(16)
Wang, X., Ge, X., Qin, Y., Liu, D., Chen, C. (2022) Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish. Frontiers in Physiology. 13:919579
Qian, F., Wei, G., Gao, Y., Wang, X., Gong, J., Guo, C., Wang, X., Zhang, X., Zhao, J., Wang, C., Xu, M., Hu, Y., Yin, G., Kang, J., Chai, R., Xie, G., Liu, D. (2022) Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cellular and molecular life sciences : CMLS. 79:385
Duan, X., Shi, Y., Zhao, S., Yao, L., Sheng, J., Liu, D. (2022) Foxc1a regulates zebrafish vascular integrity and brain vascular development through targeting amotl2a and ctnnb1. Microvascular Research. 143:104400
Zhao, J., Wei, G., Zhu, J., Liu, D., Qin, B. (2022) Expression analysis of nel during zebrafish embryonic development. Gene expression patterns : GEP. 45:119258
Lu, Y., Tang, D., Zheng, Z., Wang, X., Zuo, N., Yan, R., Wu, C., Ma, J., Wang, C., Xu, H., He, Y., Liu, D., Liu, S. (2022) Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways. Frontiers in molecular neuroscience. 15:844668
Sheng, J., Xu, J., Geng, K., Liu, D. (2022) Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord. Frontiers in molecular neuroscience. 15:854556
Sheng, J., Gong, J., Shi, Y., Wang, X., Liu, D. (2022) MicroRNA-22 coordinates vascular and motor neuronal pathfinding via sema4 during zebrafish development. Open Biology. 12:210315
Zheng, Y.Q., Suo, G.H., Liu, D., Li, H.Y., Wu, Y.J., Ni, H. (2022) Nexmifa Regulates Axon Morphogenesis in Motor Neurons in Zebrafish. Frontiers in molecular neuroscience. 15:848257
Wei, G., Zhang, X., Cai, C., Sheng, J., Xu, M., Wang, C., Gu, Q., Guo, C., Chen, F., Liu, D., Qian, F. (2022) Dual-Specificity Phosphatase 14 Regulates Zebrafish Hair Cell Formation Through Activation of p38 Signaling Pathway. Frontiers in Cellular Neuroscience. 16:840143
Zheng, S., Tang, D., Wang, X., Liu, C., Zuo, N., Yan, R., Wu, C., Ma, J., Wang, C., Xu, H., He, Y., Liu, D., Liu, S. (2022) Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model. Frontiers in molecular neuroscience. 15:844568
Qian, P., Kang, J., Liu, D., Xie, G. (2022) Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Frontiers in genetics. 13:851719
Wang, S., Qin, Y., Sheng, J., Duan, X., Shen, L., Liu, D. (2022) Aquaporin 8ab is required in zebrafish embryonic intestine development. Acta biochimica et biophysica Sinica. 54:1-9
Gong, J., Qian, P., Hu, Y., Guo, C., Wei, G., Wang, C., Cai, C., Wang, H., Liu, D. (2021) Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish. Frontiers in cell and developmental biology. 9:663995
Zhang, Y., Wang, Y., Yao, X., Wang, C., Chen, F., Liu, D., Shao, M., Xu, Z. (2020) Rbm24a Is Necessary for Hair Cell Development Through Regulating mRNA Stability in Zebrafish. Frontiers in cell and developmental biology. 8:604026
Shen, D., Chen, J., Liu, D., Shen, M., Wang, X., Wu, Y., Ke, S., Macdonald, R.L., Zhang, Q. (2020) The GABRG2 F343L allele causes spontaneous seizures in a novel transgenic zebrafish model that can be treated with suberanilohydroxamic acid (SAHA). Annals of translational medicine. 8:1560
Shi, L., Chen, C., Yin, Z., Wei, G., Xie, G., Liu, D. (2020) Systematic profiling of early regulators during tissue regeneration using zebrafish model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 29(1):189-195
Gong, J., Hu, S., Huang, Z., Hu, Y., Wang, X., Zhao, J., Qian, P., Wang, C., Sheng, J., Lu, X., Wei, G., Liu, D. (2020) The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish. Frontiers in molecular neuroscience. 13:34
Zhang, H., Gao, Y., Qian, P., Dong, Z., Hao, W., Liu, D., Duan, X. (2019) Expression analysis of Rab11 during zebrafish embryonic development. BMC Developmental Biology. 19:25
Gao, Y., Liu, Z., Jia, D., Hu, Q., Li, L., Tang, R., Li, D. (2019) Acute microcystin-LR exposure interfere thyroid hormones homeostasis in adult zebrafish (Danio rerio). Chemosphere. 243:125258
Zhang, Z., Hou, H., Yu, S., Zhou, C., Zhang, X., Li, N., Zhang, S., Song, K., Lu, Y., Liu, D., Lu, H., Xu, H. (2019) Inflammation-induced mammalian target of rapamycin signaling is essential for retina regeneration. Glia. 68(1):111-127
Shi, Y., Wang, X., Shi, Y., Zhang, J., Zhao, S., Yin, Z., Xu, G., Duan, X., Guo, Z., Liang, X., Liu, D. (2019) Two Compounds Isolated From Ganglioside GM1 Promote Angiogenesis in Zebrafish. Journal of Cardiovascular Pharmacology. 74:71-79
Liao, S., Han, L., Zheng, X., Wang, X., Zhang, P., Wu, J., Liu, R., Fu, Y., Sun, J., Kang, X., Liu, K., Fan, T., Li, S., Zheng, X. (2019) Tanshinol borneol ester (DBZ), a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris. British journal of pharmacology. 176(17):3143-3160
Qin, Y., Wang, S., Duan, X., Liu, D. (2019) Expression analysis of the aquaporins during zebrafish embryonic development. Gene expression patterns : GEP. 32:38-43
Zhang, K., Zhang, H., Zhou, H., Crookes, D., Li, L., Shao, Y., Liu, D. (2019) Zebrafish Embryo Vessel Segmentation Using a Novel Dual ResUNet Model. Computational intelligence and neuroscience. 2019:8214975
Shi, Y., Duan, X., Xu, G., Wang, X., Wei, G., Dong, S., Xie, G., Liu, D. (2019) A ribosomal DNA-hosted microRNA regulates zebrafish embryonic angiogenesis. Angiogenesis. 22(2):211-221
Dong, Z., Wu, S., Zhu, C., Wang, X., Li, Y., Chen, X., Liu, D., Qiang, L., Baas, P.W., Liu, M. (2018) CRISPR/Cas9-mediated kif15 mutations accelerate axonal outgrowth during neuronal development and regeneration in zebrafish. Traffic (Copenhagen, Denmark). 20(1):71-81
Gong, J., Chai, L., Xu, G., Ni, Y., Liu, D. (2018) The expression of natriuretic peptide receptors in developing zebrafish embryos. Gene expression patterns : GEP. 29:65-71
Liu, Z.Z., Zhu, J., Wang, C.L., Wang, X., Han, Y.Y., Liu, L.Y., Xu, H.A. (2018) CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons. Neural Plasticity. 2018:8791304
Bao, L., You, B., Shi, S., Shan, Y., Zhang, Q., Yue, H., Zhang, J., Zhang, W., Shi, Y., Liu, Y., Wang, X., Liu, D., You, Y. (2018) Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10. Oncogene. 37(21):2873-2889
Chen, Z., Shao, X.Y., Wang, C., Hua, M.H., Wang, C.N., Wang, X., Wang, Q.J., Yao, J.Y., Fan, Y.H., Qin, Y.W. (2018) Mycobacterium marinum Infection in Zebrafish and Microglia Imitates the Early Stage of Tuberculous Meningitis. Journal of molecular neuroscience : MN. 64(2):321-330
Gao, Y., Liu, J., Wang, X., Liu, D. (2017) [Genetic manipulation in zebrafish]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 33:1674-1692
Jin, D., Zhu, D., Fang, Y., Chen, Y., Yu, G., Pan, W., Liu, D., Li, F., Zhong, T.P. (2017) Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures. Journal of genetics and genomics = Yi chuan xue bao. 44(10):483-492
Gong, J., Wang, X., Zhu, C., Dong, X., Zhang, Q., Wang, X., Duan, X., Qian, F., Shi, Y., Gao, Y., Zhao, Q., Chai, R., Liu, D. (2017) Insm1a Regulates Motor Neuron Development in Zebrafish. Frontiers in molecular neuroscience. 10:274
He, Y., Lu, X., Qian, F., Liu, D., Chai, R., Li, H. (2017) Insm1a Is Required for Zebrafish Posterior Lateral Line Development.. Frontiers in molecular neuroscience. 10:241
Wang, F., Liu, D., Zhang, R.R., Yu, L.W., Zhao, J.Y., Yang, X.Y., Jiang, S.S., Ma, D., Qiao, B., Zhang, F., Jin, L., Gui, Y.H., Wang, H.Y. (2017) A TBX5 3'UTR variant increases the risk of congenital heart disease in the Han Chinese population. Cell discovery. 3:17026
Zhang, J., Qi, J., Wu, S., Peng, L., Shi, Y., Yang, J., Yin, Z., Gao, Y., Wang, C., Gong, J., Zhang, H., Zhang, J., Liu, D. (2017) Fatty Acid Binding Protein 11a Is Required for Brain Vessel Integrity in Zebrafish. Frontiers in Physiology. 8:214
Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Corrigendum: Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:44970
Zhang, J.J., Wang, X., Liu, D. (2017) [Natriuretic peptide precursor C coding gene contributes to zebrafish angiogenesis]. Sheng li xue bao : [Acta physiologica Sinica]. 69:11-16
Lv, F., Zhu, C., Yan, X., Wang, X., Liu, D. (2017) Generation of a mef2aa:EGFP transgenic zebrafish line that expresses EGFP in muscle cells. Fish physiology and biochemistry. 43(1):287-294
Mu, Z., Zhang, S., He, C., Hou, H., Liu, D., Hu, N., Xu, H. (2017) Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration. Neuroscience Bulletin. 33(1):53-61
Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:40815
Lin, Q., Fan, S., Zhang, Y., Xu, M., Zhang, H., Yang, Y., Lee, A.P., Woltering, J.M., Ravi, V., Gunter, H.M., Luo, W., Gao, Z., Lim, Z.W., Qin, G., Schneider, R.F., Wang, X., Xiong, P., Li, G., Wang, K., Min, J., Zhang, C., Qiu, Y., Bai, J., He, W., Bian, C., Zhang, X., Shan, D., Qu, H., Sun, Y., Gao, Q., Huang, L., Shi, Q., Meyer, A., Venkatesh, B. (2016) The seahorse genome and the evolution of its specialized morphology. Nature. 540:395-399
Qi, J., Dong, Z., Shi, Y., Wang, X., Qin, Y., Wang, Y., Liu, D. (2016) NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish. Cell Research. 26(12):1349-1352
Wang, X., Yuan, W., Wang, X., Qi, J., Qin, Y., Shi, Y., Zhang, J., Gong, J., Dong, Z., Liu, X., Sun, C., Chai, R., Le Noble, F., Liu, D. (2016) The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis. Oncotarget. 7(47):77749-77763
Shi, Y.W., Yuan, W., Wang, X., Gong, J., Zhu, S.X., Chai, L.L., Qi, J.L., Qin, Y.Y., Gao, Y., Zhou, Y.L., Fan, X.L., Ji, C.Y., Wu, J.Y., Wang, Z.W., Liu, D. (2016) Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish. Scientific Reports. 6:30189
Wang, X., Ling, C.C., Li, L., Qin, Y., Qi, J., Liu, X., You, B., Shi, Y., Zhang, J., Jiang, Q., Xu, H., Sun, C., You, Y., Chai, R., Liu, D. (2016) MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovascular research. 110(1):140-50