ZFIN Lab: Bovolenta Lab

ZFIN ID: ZDB-LAB-141112-1

ZFIN ID: ZDB-LAB-141112-1

Bovolenta Lab

PI/Director:	Bovolenta, Paola
Co-PI / Senior Researcher:	Cubelos, Beatriz Esteve, Pilar
Contact Person:	Tabanera, Noemí
Email:	ntabanera@cbm.csic.es
URL:	http://web4.cbm.uam.es/joomla-rl/index.php/es/index.php?option=com_content&view=article&id=408
Address:	Centro de Biología Molecular Severo Ochoa (CSIC-UAM) C/Nicolás Cabrera, 1 Madrid (28049), Spain
Country:	Spain
Phone:	00 34 91196 4718
Fax:	00 34 91196 4420
Line Designation:	cbm

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 12 genomic features

STATEMENT OF RESEARCH INTERESTS

The vertebrate eye forms through the coordination of two major events: the progressive regionalization of the eye primordium into retina, pigmented epithelium and optic nerve, and the choreographed reorganization of eye cells to give rise to the optic cups. Since 1997 in the Instituto Cajal and from 2011 in the CBMSO, our group has contributed to elucidate the genetic cascade controlling eye specification and differentiation. Our experimental approach is multidisciplinary and involves the use of biochemistry, cell and molecular biology, experimental embryology, transgenesis and gain/loss-of function studies, applied to mouse, chick and teleost fishes. For more information on our current research, see http://web4.cbm.uam.es/joomla-rl/index.php/es/index.php?option=com_content&view=article&id=408

LAB MEMBERS

Cardozo, Marcos Post-Doc	Di Marco, Francisco Post-Doc	DiMeglio, Thomas Post-Doc
Sánchez-Arrones, Luisa Post-Doc	Durán-Trío, Lara Graduate Student	Hernández-Bejarano, María Graduate Student
Mateo-Ruiz, Inés Graduate Student	Moreno-Mármol, Tania Graduate Student	Nieto-López, Francisco Graduate Student
Ramón Perea, Juan Graduate Student	Rueda-Carrasco, Javier Graduate Student	Sanz-Rodríguez, Miriam Graduate Student
Tabanera, Noemí Research Staff	Bermejo, M. Jesús Technical Staff	Sandonís, Africa Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Camacho-Macorra, C., Tabanera, N., Sánchez-Bustamante, E., Bovolenta, P., Cardozo, M.J. (2024) Maternal vgll4a regulates zebrafish epiboly through Yap1 activity. Frontiers in cell and developmental biology. 12:13626951362695

Hernández-Bejarano, M., Gestri, G., Monfries, C., Tucker, L., Dragomir, E.I., Bianco, I.H., Bovolenta, P., Wilson, S.W., Cavodeassi, F. (2022) Foxd1-dependent induction of a temporal retinal character is required for visual function. Development (Cambridge, England). 149(24):

Camacho-Macorra, C., Sintes, M., Tabanera, N., Grasa, I., Bovolenta, P., Cardozo, M.J. (2021) Mosmo Is Required for Zebrafish Craniofacial Formation. Frontiers in cell and developmental biology. 9:767048

Moreno-Mármol, T., Ledesma-Terrón, M., Tabanera, N., Martin-Bermejo, M.J., Cardozo, M.J., Cavodeassi, F., Bovolenta, P. (2021) Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis. eLIFE. 10:

Buono, L., Corbacho, J., Naranjo, S., Almuedo-Castillo, M., Moreno-Marmol, T., de la Cerda, B., Sanbria-Reinoso, E., Polvillo, R., Díaz-Corrales, F.J., Bogdanovic, O., Bovolenta, P., Martínez-Morales, J.R. (2021) Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. Nature communications. 12:3866

Oprişoreanu, A.M., Smith, H.L., Arya, S., Webster, R., Zhong, Z., Wehner, D., Cardozo, M.J., Becker, T., Talbot, K., Becker, C.G. (2019) Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Reports. 29:1082-1098.e10

Bertolini, J.A., Favaro, R., Zhu, Y., Pagin, M., Ngan, C.Y., Wong, C.H., Tjong, H., Vermunt, M.W., Martynoga, B., Barone, C., Mariani, J., Cardozo, M.J., Tabanera, N., Zambelli, F., Mercurio, S., Ottolenghi, S., Robson, P., Creyghton, M.P., Bovolenta, P., Pavesi, G., Guillemot, F., Nicolis, S.K., Wei, C.L. (2019) Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance. Cell Stem Cell. 24:462-476.e6

Moreno-Marmol, T., Cavodeassi, F., Bovolenta, P. (2018) Setting Eyes on the Retinal Pigment Epithelium. Frontiers in cell and developmental biology. 6:145

Cardozo, M.J., Mysiak, K.S., Becker, T., Becker, C.G. (2017) Reduce, Reuse, Recycle - Developmental Signals in Spinal Cord Regeneration. Developmental Biology. 432(1):53-62

Shah, M.H., Tabanera, N., Krishnadas, S.R., Pillai, M.R., Bovolenta, P., Sundaresan, P. (2017) Identification and characterization of variants and a novel 4 bp deletion in the regulatory region of SIX6, a risk factor for primary open-angle glaucoma.. Molecular genetics & genomic medicine. 5:323-335

Albuixech-Crespo, B., López-Blanch, L., Burguera, D., Maeso, I., Sánchez-Arrones, L., Moreno-Bravo, J.A., Somorjai, I., Pascual-Anaya, J., Puelles, E., Bovolenta, P., Garcia-Fernàndez, J., Puelles, L., Irimia, M., Ferran, J.L. (2017) Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. PLoS Biology. 15:e2001573

Mandriani, B., Castellana, S., Rinaldi, C., Manzoni, M., Venuto, S., Rodriguez-Aznar, E., Galceran, J., Nieto, M.A., Borsani, G., Monti, E., Mazza, T., Merla, G., Micale, L. (2016) Identification of p53-target genes in Danio rerio. Scientific Reports. 6:32474

Hernández-Bejarano, M., Gestri, G., Spawls, L., Nieto-López, F., Picker, A., Tada, M., Brand, M., Bovolenta, P., Wilson, S.W., Cavodeassi, F. (2015) Opposing Shh and Fgf signals initiate nasotemporal patterning of the retina. Development (Cambridge, England). 142(22):3933-42

Gómez-Marín, C., Tena, J.J., Acemel, R.D., López-Mayorga, M., Naranjo, S., de la Calle-Mustienes, E., Maeso, I., Beccari, L., Aneas, I., Vielmas, E., Bovolenta, P., Nobrega, M.A., Carvajal, J., Gómez-Skarmeta, J.L. (2015) Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders. Proceedings of the National Academy of Sciences of the United States of America. 112(24):7542-7

Cardozo, M.J., Sánchez-Arrones, L., Sandonis, A., Sánchez-Camacho, C., Gestri, G., Wilson, S.W., Guerrero, I., Bovolenta, P. (2014) Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Nature communications. 5:4272

Martínez-Morales, J.R., Rodrigo, I., and Bovolenta, P. (2004) Eye development: a view from the retina pigmented epithelium. BioEssays : news and reviews in molecular, cellular and developmental biology. 26(7):766-777