ZFIN Lab: Özhan Lab

ZFIN ID: ZDB-LAB-140513-1

Özhan Lab

PI/Director:	Özhan, Günes
Contact Person:	Özhan, Günes
Email:	gunes.ozhan@ibg.org.tr
URL:	http://ozhanlab.com
Address:	Izmir Biomedicine and Genome Center (IBG) Dokuz Eylul University Health Campus Mithatpasa St. No: 58/5 Balcova 35340 - Izmir / TURKEY
Country:	Turkey
Phone:	0090 531 272 2399
Fax:	0090 232 412 6509
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Cakan-Akdogan, Gülcin Post-Doc

Azbazdar, Yagmur Graduate Student

Kartal, Asli Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Saygili, E., Ersoz-Gulseven, E., Kıbrıs, E., Cakan-Akdogan, G., Ucuncu, M. (2024) A novel 2-aminophenalenone-based fluorescent probe designed for monitoring H₂O₂ for in vitro and in vivo bioimaging. Talanta. 271:125669125669

Guzelkaya, M., Onal, E., Gelinci, E., Kumral, A., Cakan-Akdogan, G. (2023) A zebrafish model for studying the mechanisms of newborn hyperbilirubinemia and bilirubin-induced neurological damage. Frontiers in cell and developmental biology. 11:12754141275414

Argitekin, E., Ersoz-Gulseven, E., Cakan-Akdogan, G., Akdogan, Y. (2023) Dopamine-Conjugated Bovine Serum Albumin Nanoparticles Containing pH-Responsive Catechol-V(III) Coordination for In Vitro and In Vivo Drug Delivery. Biomacromolecules. 24(8):3603-3618

Azbazdar, Y., Poyraz, Y.K., Ozalp, O., Nazli, D., Ipekgil, D., Cucun, G., Ozhan, G. (2023) High-fat diet feeding triggers a regenerative response in the adult zebrafish brain. Molecular neurobiology. 60(5):2486-2506

Arslan, M., Karadag, M., Onal, E., Gelinci, E., Cakan-Akdogan, G., Kalyoncu, S. (2022) Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv. Scientific Reports. 12:5449

Dhasmana, D., Veerapathiran, S., Azbazdar, Y., Nelanuthala, A.V.S., Teh, C., Ozhan, G., Wohland, T. (2021) Wnt3 Is Lipidated at Conserved Cysteine and Serine Residues in Zebrafish Neural Tissue. Frontiers in cell and developmental biology. 9:671218

Azbazdar, Y., Ozalp, O., Sezgin, E., Veerapathiran, S., Duncan, A.L., Sansom, M.S.P., Eggeling, C., Wohland, T., Karaca, E., Ozhan, G. (2019) More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains. Frontiers in cell and developmental biology. 7:281

Gunes, A., Bagirsakci, E., Iscan, E., Cakan-Akdogan, G., Aykutlu, U., Senturk, S., Ozhan, G., Erdal, E., Nart, D., Barbet, F.Y., Atabey, N. (2018) Thioredoxin interacting protein promotes invasion in hepatocellular carcinoma. Oncotarget. 9:36849-36866

Sezgin, E., Azbazdar, Y., Ng, X.W., Teh, C., Simons, K., Weidinger, G., Wohland, T., Eggeling, C., Ozhan, G. (2017) Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments. The FEBS journal. 284:2513-2526

Özhan, G., Weidinger, G. (2015) Wnt/β-catenin signaling in heart regeneration. Cell regeneration (London, England). 4:3

Kizil, C., Küchler, B., Yan, J.J., Özhan, G., Moro, E., Argenton, F., Brand, M., Weidinger, G., Antos, C.L. (2014) Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development (Cambridge, England). 141:3529-39

Wehner, D., Cizelsky, W., Vasudevaro, M.D., Özhan, G., Haase, C., Kagermeier-Schenk, B., Röder, A., Dorsky, R.I., Moro, E., Argenton, F., Kühl, M., and Weidinger, G. (2014) Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin. Cell Reports. 6(3):467-481

Luz, M., Spannl-Müller, S., Özhan, G., Kagermeier-Schenk, B., Rhinn, M., Weidinger, G., and Brand, M. (2014) Dynamic Association with Donor Cell Filopodia and Lipid-Modification Are Essential Features of Wnt8a during Patterning of the Zebrafish Neuroectoderm. PLoS One. 9(1):e84922

Özhan, G., Sezgin, E., Wehner, D., Pfister, A.S., Kühl, S.J., Kagermeier-Schenk, B., Kühl, M., Schwille, P., and Weidinger, G. (2013) Lypd6 Enhances Wnt/beta-Catenin Signaling by Promoting Lrp6 Phosphorylation in Raft Plasma Membrane Domains. Developmental Cell. 26(4):331-345

Thieme, S., Gyárfás, T., Richter, C., Özhan, G., Fu, J., Alexopulou, D., Muders, M.H., Michalk, I., Jakob, C., Dahl, A., Klink, B., Bandola, J., Bachmann, M., Schröck, E., Buchholz, F., Stewart, A.F., Weidinger, G., Anastassiadis, K., and Brenner, S. (2013) The histone demethylase UTX regulates stem cell migration and hematopoiesis. Blood. 121(13):2462-2473

Moro, E., Özhan, G., Mongera, A., Beis, D., Wierzbicki, C., Young, R.M., Bournele, D., Domenichini, A., Valdivia, L.E., Lum, L., Chen, C., Amatruda, J.F., Tiso, N., Weidinger, G., and Argenton, F. (2012) In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Developmental Biology. 366(2):327-340

Kagermeier-Schenk, B., Wehner, D., Ozhan-Kizil, G., Yamamoto, H., Li, J., Kirchner, K., Hoffmann, C., Stern, P., Kikuchi, A., Schambony, A., and Weidinger, G. (2011) Waif1/5T4 Inhibits Wnt/β-Catenin Signaling and Activates Noncanonical Wnt Pathways by Modifying LRP6 Subcellular Localization. Developmental Cell. 21(6):1129-43