ZFIN ID: ZDB-LAB-120302-1
Mostowy Lab
PI/Director: Mostowy, Serge
Contact Person: Mostowy, Serge
Email: s.mostowy@imperial.ac.uk
URL: http://www1.imperial.ac.uk/departmentofmedicine/divisions/infectiousdiseases/microbiology/hostdefence/
Address: Level 2 Flowers Building South Kensington Imperial College London SW7 2AZ UK
Country: United Kingdom
Phone: +44 (0)20 7594 3072
Fax: +44 (0)20 7594 3095
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS
The cell biology of zebrafish infection.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Yakimovich, A., Huttunen, M., Samolej, J., Clough, B., Yoshida, N., Mostowy, S., Frickel, E.M., Mercer, J. (2020) Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection. mSphere. 5(5):
Ulhuq, F.R., Gomes, M.C., Duggan, G.M., Guo, M., Mendonca, C., Buchanan, G., Chalmers, J.D., Cao, Z., Kneuper, H., Murdoch, S., Thomson, S., Strahl, H., Trost, M., Mostowy, S., Palmer, T. (2020) A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition. Proceedings of the National Academy of Sciences of the United States of America. 117(34):20836-20847
Yoshida, N., Domart, M.C., Peddie, C.J., Yakimovich, A., Mazon-Moya, M.J., Hawkins, T.A., Collinson, L., Mercer, J., Frickel, E.M., Mostowy, S. (2020) The zebrafish as a novel model for the in vivo study of Toxoplasma gondii replication and interaction with macrophages. Disease models & mechanisms. 13(7):
Torraca, V., Kaforou, M., Watson, J., Duggan, G.M., Guerrero-Gutierrez, H., Krokowski, S., Hollinshead, M., Clarke, T.B., Mostowy, R.J., Tomlinson, G.S., Sancho-Shimizu, V., Clements, A., Mostowy, S. (2019) Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. PLoS pathogens. 15:e1008006
Gomes, M.C., Mostowy, S. (2019) The Case for Modeling Human Infection in Zebrafish. Trends in microbiology. 28(1):10-18
Torraca, V., Gomes, M.C., Sarris, M., Mostowy, S. (2019) Meeting report: Zebrafish Infection and Immunity 2019. Lab animal. 48:284-287
Mickiewicz, K.M., Kawai, Y., Drage, L., Gomes, M.C., Davison, F., Pickard, R., Hall, J., Mostowy, S., Aldridge, P.D., Errington, J. (2019) Possible role of L-form switching in recurrent urinary tract infection. Nature communications. 10:4379
Price, R.L., Bugeon, L., Mostowy, S., Makendi, C., Wren, B.W., Williams, H.D., Willcocks, S.J. (2019) In vitro and in vivo properties of the bovine antimicrobial peptide, Bactenecin 5. PLoS One. 14:e0210508
Mostowy, S., Ewers, H. (2019) Editorial overview: The molecular and cellular biology of septins. Cytoskeleton (Hoboken, N.J.). 76:5-6
Willis, A.R., Torraca, V., Gomes, M.C., Shelley, J., Mazon-Moya, M., Filloux, A., Lo Celso, C., Mostowy, S. (2018) Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection.. mBio. 9(3)
Inglesfield, S., Jasiulewicz, A., Hopwood, M., Tyrrell, J., Youlden, G., Mazon-Moya, M., Millington, O.R., Mostowy, S., Jabbari, S., Voelz, K. (2018) Robust Phagocyte Recruitment Controls the Opportunistic Fungal Pathogen Mucor circinelloides in Innate Granulomas In Vivo.. mBio. 9(2)
Duggan, G.M., Mostowy, S. (2018) Use of zebrafish to study Shigella infection.. Disease models & mechanisms. 11(2)
Yoshida, N., Frickel, E.M., Mostowy, S. (2017) Macrophage-Microbe Interactions: Lessons from the Zebrafish Model. Frontiers in immunology. 8:1703
Torraca, V., Mostowy, S. (2017) Zebrafish Infection: From Pathogenesis to Cell Biology. Trends in cell biology. 28(2):143-156
Mazon-Moya, M.J., Willis, A.R., Torraca, V., Boucontet, L., Shenoy, A.R., Colucci-Guyon, E., Mostowy, S. (2017) Septins restrict inflammation and protect zebrafish larvae from Shigella infection. PLoS pathogens. 13:e1006467
Liew, N., Mazon Moya, M.J., Wierzbicki, C.J., Hollinshead, M., Dillon, M.J., Thornton, C.R., Ellison, A., Cable, J., Fisher, M.C., Mostowy, S. (2017) Chytrid fungus infection in zebrafish demonstrates that the pathogen can parasitize non-amphibian vertebrate hosts. Nature communications. 8:15048
McCarthy, R.R., Mazon-Moya, M.J., Moscoso, J.A., Hao, Y., Lam, J.S., Bordi, C., Mostowy, S., Filloux, A. (2017) Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion. Nature microbiology. 2:17027
Mesquita, F.S., Brito, C., Mazon Moya, M.J., Pinheiro, J.C., Mostowy, S., Cabanes, D., Sousa, S. (2017) Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins. EMBO reports. 18:303-318
Willis, A.R., Moore, C., Mazon-Moya, M., Krokowski, S., Lambert, C., Till, R., Mostowy, S., Sockett, R.E. (2016) Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae. Current biology : CB. 26(24):3343-3351
Shah, A., Kannambath, S., Herbst, S., Rogers, A., Soresi, S., Carby, M., Reed, A., Mostowy, S., Fisher, M.C., Shaunak, S., Armstrong-James, D.P. (2016) Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus During Macrophage Cell Death. American Journal of Respiratory and Critical Care Medicine. 194(9):1127-1139
Willis, A., Mazon-Moya, M., Mostowy, S. (2016) Investigation of septin biology in vivo using zebrafish. Methods in cell biology. 136:221-41
Herbst, S., Shah, A., Mazon Moya, M., Marzola, V., Jensen, B., Reed, A., Birrell, M.A., Saijo, S., Mostowy, S., Shaunak, S., Armstrong-James, D. (2015) Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Molecular Medicine. 7(3):240-58
Mazon Moya, M.J., Colucci-Guyon, E., Mostowy, S. (2014) Use of Shigella flexneri to Study Autophagy-Cytoskeleton Interactions. Journal of visualized experiments : JoVE. (91):e51601
Mostowy, S., Boucontet, L., Mazon Moya, M.J., Sirianni, A., Boudinot, P., Hollinshead, M., Cossart, P., Herbomel, P., Levraud, J.P., and Colucci-Guyon, E. (2013) The Zebrafish as a New Model for the In Vivo Study of Shigella flexneri Interaction with Phagocytes and Bacterial Autophagy. PLoS pathogens. 9(9):e1003588