ZFIN ID: ZDB-LAB-070619-2
Leonor Saude Lab
PI/Director: Saude, Leonor
Contact Person: Saude, Leonor
Email: msaude@medicina.ulisboa.pt
URL: http://www.imm.fm.ul.pt/web/imm/udev
Address: Instituto de Medicina Molecular Av. Prof. Egas Moniz Edifício Egas Moniz Lisboa 1649-028 Portugal
Country: Portugal
Phone: +351 217999498
Fax: +351 217999504
Line Designation: imm

Show all 5 genomic features


Fior, Rita Post-Doc Mendes, Raquel Research Staff David, Tiago

Dal Forno, G.M., Latocheski, E., Beatriz Machado, A., Becher, J., Dunsmore, L., St John, A.L., Oliveira, B.L., Navo, C.D., Jiménez-Osés, G., Fior, R., Domingos, J.B., Bernardes, G.J.L. (2023) Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions. Journal of the American Chemical Society. 145(19):10790-10799
Cruz-Duarte, R., de Almeida, C.R., Negrão, M., Fernandes, A., Borralho, P., Sobral, D., Gallego-Paez, L.M., Machado, D., Gramaça, J., Vílchez, J., Xavier, A.T., Godinho Ferreira, M., Miranda, A.R., Mansinho, H., Brito, M.J., Pacheco, T.R., Abreu, C., Lucia-Costa, A., Mansinho, A., Fior, R., Costa, L., Martins, M. (2022) Predictive and therapeutic implications of a novel PLCγ1/SHP2-driven mechanism of cetuximab resistance in metastatic colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 28(6):1203-1216
Albuquerque, C., Vanneschi, L., Henriques, R., Castelli, M., Póvoa, V., Fior, R., Papanikolaou, N. (2021) Object detection for automatic cancer cell counting in zebrafish xenografts. PLoS One. 16:e0260609
Tavares Barroso, M., Costa, B., Rebelo de Almeida, C., Castillo Martin, M., Couto, N., Carvalho, T., Fior, R. (2021) Establishment of Pancreatobiliary Cancer Zebrafish Avatars for Chemotherapy Screening. Cells. 10(8):
Póvoa, V., Rebelo de Almeida, C., Maia-Gil, M., Sobral, D., Domingues, M., Martinez-Lopez, M., de Almeida Fuzeta, M., Silva, C., Grosso, A.R., Fior, R. (2021) Innate immune evasion revealed in a colorectal zebrafish xenograft model. Nature communications. 12:1156
Pascoal, S., Grissenberger, S., Scheuringer, E., Fior, R., Ferreira, M.G., Distel, M. (2021) Using Zebrafish Larvae as a Xenotransplantation Model to Study Ewing Sarcoma. Methods in molecular biology (Clifton, N.J.). 2226:243-255
Varanda, A.B., Martins-Logrado, A., Ferreira, M.G., Fior, R. (2020) Zebrafish Xenografts Unveil Sensitivity to Olaparib beyond BRCA Status. Cancers. 12(7)
Rebelo de Almeida, C., Mendes, R.V., Pezzarossa, A., Gago, J., Carvalho, C., Alves, A., Nunes, V., Brito, M.J., Cardoso, M.J., Ribeiro, J., Cardoso, F., Ferreira, M.G., Fior, R. (2020) Zebrafish xenografts as a fast screening platform for bevacizumab cancer therapy. Communications biology. 3:299
Oliveira, B.L., Stenton, B.J., V B, U., de Almeida, C.R., Conde, J., Negrão, M., Schneider, F.S.S., Cordeiro, C., Godinho Ferreira, M., Caramori, G.F., Domingos, J.B., Fior, R., Bernardes, G.J.L. (2020) Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation. Journal of the American Chemical Society. 142(24):10869-10880
Basti, A., Fior, R., Yalҫin, M., Póvoa, V., Astaburuaga, R., Li, Y., Naderi, J., Godinho Ferreira, M., Relógio, A. (2020) The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon Cancer Model. Cancers. 12(4):
Costa, B., Estrada, M.F., Mendes, R.V., Fior, R. (2020) Zebrafish Avatars towards Personalized Medicine-A Comparative Review between Avatar Models. Cells. 9(2):
Poté, N., Cros, J., Laouirem, S., Raffenne, J., Negrão, M., Albuquerque, M., Bedossa, P., Godinho Ferreira, M., Ait Si Ali, S., Fior, R., Paradis, V. (2020) The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma. Liver international : official journal of the International Association for the Study of the Liver. 40(4):956-967
Costa, B., Ferreira, S., Póvoa, V., Cardoso, M.J., Vieira, S., Stroom, J., Fidalgo, P., Rio-Tinto, R., Figueiredo, N., Parés, O., Greco, C., Ferreira, M.G., Fior, R. (2019) Developments in zebrafish avatars as radiotherapy sensitivity reporters - towards personalized medicine. EBioMedicine. 51:102578
Fernandes, S.F., Fior, R., Pinto, F., Gama-Carvalho, M., Saúde, L. (2018) Fine-tuning of fgf8a expression through alternative polyadenylation has a selective impact on Fgf-associated developmental processes. Biochimica et biophysica acta.
Pinto, R.A., Almeida-Santos, J., Lourenço, R., Saúde, L. (2018) Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach. BMC Developmental Biology. 18:14
Fior, R., Ferreira, M.G. (2018) Reply to Katsu and Baker: Using zebrafish PDX to screen drug sensitivity of endocrine-dependent cancers. Proceedings of the National Academy of Sciences of the United States of America. 115(13):E2910
Ribeiro, A., Monteiro, J.F., Certal, A.C., Cristovão, A.M., Saúde, L. (2017) Foxj1a is expressed in ependymal precursors, controls central canal position and is activated in new ependymal cells during regeneration in zebrafish. Open Biology. 7(11)
Lopes, S.S., Distel, M., Linker, C., Fior, R., Monteiro, R., Bianco, I.H., Portugues, R., Strähle, U., Saúde, L. (2016) Report of the 4th European Zebrafish Principal Investigator Meeting. Zebrafish. 13(6):590-595
Fior, R., Maxwell, A.A., Ma, T.P., Vezzaro, A., Moens, C.B., Amacher, S.L., Lewis, J., and Saúde, L. (2012) The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1. Development (Cambridge, England). 139(24):4656-4665
Azevedo, A.S., Sousa, S., Jacinto, A., and Saude, L. (2012) An amputation resets positional information to a proximal identity in the regenerating zebrafish caudal fin. BMC Developmental Biology. 12(1):24
Cutty, S.J., Fior, R., Henriques, P.M., Saude, L., and Wardle, F.C. (2012) Identification and expression analysis of two novel members of the Mesp family in zebrafish. The International journal of developmental biology. 56(4):285-294
Lourenço, R., Lopes, S.S., and Saude, L. (2010) Left-Right Function of dmrt2 Genes Is Not Conserved between Zebrafish and Mouse. PLoS One. 5(12):e14438
Lopes, S.S., Lourenço, R., Pacheco, L., Moreno, N., Kreiling, J., and Saude, L. (2010) Notch signalling regulates left-right asymmetry through ciliary length control. Development (Cambridge, England). 137(21):3625-3632
Saúde, L., Lourenço, R., Gonçalves, A., and Palmeirim, I. (2005) terra is a left-right asymmetry gene required for left-right synchronization of the segmentation clock. Nature cell biology. 7(9):918-920
Coutinho, P., Parsons, M.J., Thomas, K.A., Hirst, E.M., Saude, L., Campos, I., Williams, P.H., Stemple, D.L. (2004) Differential Requirements for COPI Transport during Vertebrate Early Development. Developmental Cell. 7(4):547-558
Feldman, B., Concha, M.L., Saude, L., Parsons, M.J., Adams, R.J., Wilson, S.W., and Stemple, D.L. (2002) Lefty antagonism of squint is essential for normal gastrulation. Current biology : CB. 12(24):2129-2135
Parsons, M.J., Pollard, S.M., Saude, L., Feldman, B., Coutinho, P., Hirst, E.M., and Stemple, D.L. (2002) Zebrafish mutants identify an essential role for laminins in notochord formation. Development (Cambridge, England). 129(13):3137-3146
Saude, L., Woolley, K., Martin, P., Driever, W., and Stemple, D.L. (2000) Axis-inducing activities and cell fates of the zebrafish organizer. Development (Cambridge, England). 127(16):3407-3417
Heisenberg, C.P., Tada, M., Rauch, G.J., Saude, L., Concha, M.L., Geisler, R., Stemple, D.L., Smith, J.C., and Wilson, S.W. (2000) Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature. 405(6782):76-81