ZFIN Lab: Gregory Cole Lab

ZFIN ID: ZDB-LAB-070228-1

Gregory Cole Lab

PI/Director:	Cole, Gregory J.
Contact Person:	Cole, Gregory J.
Email:	gcole@nccu.edu
URL:
Address:	Julius L. Chambers Biomedical/Biotechnology Research Institute North Carolina Central University 700 George Street Durham, NC 27707
Country:	United States
Phone:	919-530-7028
Fax:	919-530-7760
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 1 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Zhang, C., Ezem, N., Mackinnon, S., Cole, G.J. (2023) Embryonic Ethanol but Not Cannabinoid Exposure Affects Zebrafish Cardiac Development via Agrin and Sonic Hedgehog Interaction. Cells. 12(9):

Burton, D.F., Boa-Amponsem, O.M., Dixon, M.S., Hopkins, M.J., Herbin, T.A., Toney, S., Tarpley, M., Rodriguez, B.V., Fish, E.W., Parnell, S.E., Cole, G.J., Williams, K.P. (2022) Pharmacological activation of the Sonic hedgehog pathway with a Smoothened small molecule agonist ameliorates the severity of alcohol-induced morphological and behavioral birth defects in a zebrafish model of fetal alcohol spectrum disorder. Journal of neuroscience research. 100(8):1585-1601

Fish, E.W., Murdaugh, L.B., Zhang, C., Boschen, K.E., Boa-Amponsem, O., Mendoza-Romero, H.N., Tarpley, M., Chdid, L., Mukhopadhyay, S., Cole, G.J., Williams, K.P., Parnell, S.E. (2019) Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. Scientific Reports. 9:16057

Boa-Amponsem, O., Zhang, C., Mukhopadhyay, S., Ardrey, I., Cole, G.J. (2019) Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model. Birth defects research. 111(12):775-788

Zhang, C., Boa-Amponsem, O., Cole, G.J. (2017) Comparison of molecular marker expression in early zebrafish brain development following chronic ethanol or morpholino treatment. Experimental brain research. 235(8):2413-2423

Burton, D., Zhang, C., Boa-Amponsem, O., Mackinnon, S., Cole, G.J. (2017) Long-term behavioral change as a result of acute ethanol exposure in zebrafish: Evidence for a role for sonic hedgehog but not retinoic acid signaling. Neurotoxicology and teratology. 61:66-73

Zhang, C., Anderson, A., Cole, G.J. (2015) Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish. Birth defects research. Part A, Clinical and molecular teratology. 103(12):1046-57

Bailey, J.M., Oliveri, A.N., Zhang, C., Frazier, J.M., Mackinnon, S., Cole, G.J., Levin, E.D. (2015) Long-term Behavioral Impairment Following Acute Embryonic Ethanol Exposure in Zebrafish. Neurotoxicology and teratology. 48:1-8

Zhang, C., Frazier, J.M., Chen, H., Liu, Y., Lee, J.A., Cole, G.J. (2014) Molecular and morphological changes in zebrafish following transient ethanol exposure during defined developmental stages. Neurotoxicology and teratology. 44:70-80

Hu, B., Chen, H., Liu, X., Zhang, C., Cole, G.J., Lee, J.A., and Chen, X. (2013) Transgenic Overexpression of cdx1b Induces Metaplastic Changes of Gene Expression in Zebrafish Esophageal Squamous Epithelium. Zebrafish. 10(2):218-227

Zhang, C., Ojiaku, P., and Cole, G.J. (2013) Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. Birth defects research. Part A, Clinical and molecular teratology. 97(1):8-27

Cole, G.J., Zhang, C., Ojiaku, P., Bell, V., Devkota, S., and Mukhopadhyay, S. (2012) Effects of ethanol exposure on nervous system development in zebrafish. International review of cell and molecular biology. 299:255-315

Xiao, T., Staub, W., Robles, E., Gosse, N.J., Cole, G.J., and Baier, H. (2011) Assembly of Lamina-Specific Neuronal Connections by Slit Bound to Type IV Collagen. Cell. 146(1):164-176

Zhang, C., Turton, Q.M., Mackinnon, S., Sulik, K.K., and Cole, G.J. (2011) Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. Birth defects research. Part A, Clinical and molecular teratology. 91(3):129-141

Hu, B., Zhang, C., Baawo, K., Qin, R., Cole, G.J., Lee, J.A., and Chen, X. (2010) Zebrafish K5 promoter driven GFP expression as a transgenic system for oral research. Oral oncology. 46(1):31-37

Lee, J.A., Anholt, R.R., and Cole, G.J. (2008) Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish. Mechanisms of Development. 125(1-2):167-181

Lee, J.A., and Cole, G.J. (2007) Generation of transgenic zebrafish expressing green fluorescent protein under control of zebrafish amyloid precursor protein gene regulatory elements. Zebrafish. 4(4):277-286