ZFIN ID: ZDB-LAB-070103-1
Laboratory of Ecology and Environmental Toxicology
PI/Director: Santos, Manuel
Soares, Amadeu
Contact Person: Loureiro, Susana
Email: sloureiro@ua.pt
URL: http://www.bio.ua.pt/
Address: Department of Biology University of Aveiro Campus Universitário de Santiago 3810-193 Aveiro Portugal
Country: Portugal
Phone: +351 234370792
Fax: +351 234426408
Line Designation: None assigned


GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Pereira, Patricia Post-Doc Amorim, Monica Research Staff Ferreira, Abel Research Staff
Loureiro, Susana Research Staff Pastorinho, Ramiro Research Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Henriques, M.C., Carvalho, I., Santos, C., Herdeiro, M.T., Fardilha, M., Pavlaki, M.D., Loureiro, S. (2023) Unveiling the molecular mechanisms and developmental consequences of mercury (Hg) toxicity in zebrafish embryo-larvae: A comprehensive approach. Neurotoxicology and teratology. 100:107302107302
Barreto, A., Santos, J., Calisto, V., Rocha, L.S., Amorim, M.J.B., Maria, V.L. (2023) Cocktail effects of emerging contaminants on zebrafish: Nanoplastics and the pharmaceutical diphenhydramine. NanoImpact. 30:100456
Carneiro, D., Damasceno, É.P., Ferreira, V., Charlie-Silva, I., Tedim, J., Maia, F., Loureiro, S., Martins, R., Pavlaki, M.D. (2023) Zn-Al layered double hydroxides induce embryo malformations and impair locomotion behavior in Danio rerio. NanoImpact. 30:100457
Gabriel, A., Venâncio, C., Sousa, J.P., Leston, S., Ramos, F., Soares, A., Lopes, I. (2023) Ecotoxicity of eluates obtained from Basamid® contaminated soils is pH dependent: A study with Hydra viridissima, Xenopus laevis and Danio rerio. The Science of the total environment. 868:161640
Barreto, A., Santos, J., Capitão, A., Eusébio, R., Pinheiro Damasceno, É., Luísa Machado, A., Rocha, L.S., Calisto, V., Amorim, M.J.B., Maria, V.L. (2022) Assessment of diphenhydramine toxicity - Is its mode of action conserved between human and zebrafish?. Environment International. 164:107263
Santos, J., Barreto, A., Sousa, É.M.L., Calisto, V., Amorim, M.J.B., Maria, V.L. (2022) The role of nanoplastics on the toxicity of the herbicide phenmedipham, using Danio rerio embryos as model organisms. Environmental pollution (Barking, Essex : 1987). 303:119166
Abreu, S.N., Jesus, F., Domingues, I., Batista, F., Pereira, J.L., Serpa, D., Soares, A.M.V.M., Martins, R.E., Oliveira e Silva, M. (2022) Automated Counting of Daphnid Neonates, Artemia Nauplii and Zebrafish Eggs: A Proof of Concept. Environmental toxicology and chemistry. 41(6):1451-1458
Santos, B., Andrade, T., Domingues, I., Ribeiro, R., Soares, A.M., Lopes, I. (2021) Influence of salinity on the toxicity of copper and cadmium to Zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 241:106003
Barreto, A., Santos, J., Amorim, M.J.B., Maria, V.L. (2021) Polystyrene Nanoplastics Can Alter the Toxicological Effects of Simvastatin on Danio rerio. Toxics. 9(3):
Gonçalves, S.F., Silva, A.R.R., Pavlaki, M.D., Morgado, R.G., Loureiro, S. (2021) Site-specific hazard evaluation for improved groundwater risk assessment. Chemosphere. 274:129742
Rivero-Wendt, C.L.G., Miranda-Vilela, A.L., Domingues, I., Oliveira, R., Monteiro, M.S., Moura-Mello, M.A.M., Matias, R., Soares, A.M.V.M., Grisolia, C.K. (2020) Steroid androgen 17 alpha methyltestosterone used in fish farming induces biochemical alterations in zebrafish adults. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 55(11):1321-1332
Soares, M.P., Machado, A.L., Hayd, L., Soares, A., Domingues, I. (2020) Effects of pH and nitrites on the toxicity of a cypermethrin-based pesticide to zebrafish embryos. Environmental Toxicology and Pharmacology. 76:103351
Quintaneiro, C., Soares, A.M.V.M., Costa, D., Monteiro, M.S. (2019) Effects of PCB-77 in adult zebrafish after exposure during early life stages. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 54(5):478-483
Almeida, A.R., Jesus, F., Henriques, J.F., Andrade, T.S., Barreto, Â., Koba, O., Giang, P.T., Soares, A.M.V.M., Oliveira, M., Domingues, I. (2018) The role of humic acids on gemfibrozil toxicity to zebrafish embryos. Chemosphere. 220:556-564
Quintaneiro, C., Teixeira, B., Benedé, J.L., Chisvert, A., Soares, A.M.V.M., Monteiro, M.S. (2018) Toxicity effects of the organic UV-filter 4-Methylbenzylidene camphor in zebrafish embryos. Chemosphere. 218:273-281
Araújo, A.R.D., Melo, T., Maciel, E.A., Pereira, C., Morais, C.M., Santinha, D.R., Tavares, J.F., Oliveira, H., Jurado, A.S., Costa, V., Domingues, P., Domingues, M.R.M., Santos, M.A.S. (2018) Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast. PLoS One. 13:e0202402
Meireles, G., Daam, M.A., Madeira Sanches, A.L., Zanoni, M.V.B., Soares, A.M.V.M., Gravato, C., de Oliveira, D.P. (2018) Red disperse dyes (DR 60, DR 73 and DR 78) at environmentally realistic concentrations impact biochemical profile of early life stages of zebrafish (Danio rerio). Chemico-biological interactions. 292:94-100
Loureiro, S., Gonçalves, S.F., Gonçalves, G., Hortiguela, M.J., Rebelo, S., Ferro, M.C., Vila, M. (2018) Eco-friendly profile of pegylated nano-graphene oxide at different levels of an aquatic trophic chain. Ecotoxicology and environmental safety. 162:192-200
Amorim, M.J.B., Lin, S., Schlich, K., Navas, J.M., Brunelli, A., Neubauer, N., Vilsmeier, K., Costa, A.L., Gondikas, A., Xia, T., Galbis, L., Badetti, E., Marcomini, A., Hristozov, D., Kammer, F.V., Hund-Rinke, K., Scott-Fordsmand, J.J., Nel, A., Wohlleben, W. (2018) Environmental Impacts by Fragments Released from Nanoenabled Products: A Multiassay, Multimaterial Exploration by the SUN Approach. Environmental science & technology. 52(3):1514-1524
Abe, F.R., Soares, A.M.V.M., Oliveira, D.P., Gravato, C. (2017) Toxicity of dyes to zebrafish at the biochemical level: Cellular energy allocation and neurotoxicity. Environmental pollution (Barking, Essex : 1987). 235:255-262
Abe, F.R., Gravato, C., Soares, A.M.V.M., de Oliveira, D.P. (2017) Biochemical approaches to assess oxidative stress induced by exposure to natural and synthetic dyes in early life stages in zebrafish. Journal of toxicology and environmental health. Part A. 80(23-24):1259-1268
Moura, M.A.M., Oliveira, R., Jonsson, C.M., Domingues, I., Soares, A.M.V.M., Nogueira, A.J.A. (2017) The sugarcane herbicide ametryn induces oxidative stress and developmental abnormalities in zebrafish embryos. Environmental science and pollution research international. 25(14):13416-13425
Abe, F.R., Mendonça, J.N., Moraes, L.A., Oliveira, G.A., Gravato, C., Soares, A.M., Oliveira, D.P. (2017) Toxicological and behavioral responses as a tool to assess the effects of natural and synthetic dyes on zebrafish early life. Chemosphere. 178:282-290
Quintaneiro, C., Patrício, D., Novais, S.C., Soares, A.M., Monteiro, M.S. (2017) Endocrine and physiological effects of linuron and S-metolachlor in zebrafish developing embryos. The Science of the total environment. 586:390-400
Faria, M., Prats, E., Padrós, F., Soares, A.M., Raldúa, D. (2017) Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication. Archives of toxicology. 91(4):1891-1901
Andrade, T.S., Henriques, J.F., Almeida, A.R., Soares, A.M., Scholz, S., Domingues, I. (2017) Zebrafish embryo tolerance to environmental stress factors - concentration/dose response analysis of oxygen limitation, pH and UV-light irradiation. Environmental toxicology and chemistry. 36(3):682-690
Cunha, V., Burkhardt-Medicke, K., Wellner, P., Santos, M.M., Moradas-Ferreira, P., Luckenbach, T., Ferreira, M. (2017) Effects of pharmaceuticals and personal care products (PPCPs) on multixenobiotic resistance (MXR) related efflux transporter activity in zebrafish (Danio rerio) embryos. Ecotoxicology and environmental safety. 136:14-23
Oliveira, J.M., Galhano, V., Henriques, I., Soares, A.M., Loureiro, S. (2017) Basagran® induces developmental malformations and changes the bacterial community of zebrafish embryos.. Environmental pollution (Barking, Essex : 1987). 221:52-63
Cunha, V., Santos, M.M., Moradas-Ferreira, P., Castro, L.F.C., Ferreira, M. (2017) Simvastatin modulates gene expression of key receptors in zebrafish embryos. Journal of toxicology and environmental health. Part A. 80(9):465-476
Cunha, V., Rodrigues, P., Santos, M.M., Moradas-Ferreira, P., Ferreira, M. (2016) Danio rerio embryos on Prozac - Effects on the detoxification mechanism and embryo development. Aquatic toxicology (Amsterdam, Netherlands). 178:182-189
Oliveira, R., Grisolia, C.K., Monteiro, M.S., Soares, A.M., Domingues, I. (2016) Multilevel assessment of ivermectin effects using different zebrafish life stages. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 187:50-61
Cunha, V., Santos, M.M., Moradas-Ferreira, P., Ferreira, M. (2016) Simvastatin effects on detoxification mechanisms in Danio rerio embryos. Environmental science and pollution research international. 23(11):10615-29
Garcia-Reyero, N., Escalon, L., Prats, E., Faria, M., Soares, A.M., Raldúa, D. (2016) Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Bulletin of environmental contamination and toxicology. 96(6):707-713
Matos, J.C., Soares, A.R., Domingues, I., Monteiro, G.A., Gonçalves, M.C. (2016) ORMOPLEXEs for gene therapy: In vitro and in vivo assays. Materials science & engineering. C, Materials for biological applications. 63:546-53
Rivero-Wendt, C.L., Oliveira, R., Monteiro, M.S., Domingues, I., Soares, A.M., Grisolia, C.K. (2016) Steroid androgen 17α-methyltestosterone induces malformations and biochemical alterations in zebrafish embryos. Environmental Toxicology and Pharmacology. 44:107-113
Andrade, T.S., Henriques, J.F., Almeida, A.R., Machado, A.L., Koba, O., Giang, P.T., Soares, A.M.V.M., Domingues, I. (2016) Corrigendum to "Carbendazim exposure induces developmental, biochemical and behavioural disturbance in zebrafish embryos" [Aquat. Toxicol. 170 (2016) 390-399]. Aquatic toxicology (Amsterdam, Netherlands). 173:228
Domingues, I., Oliveira, R., Soares, A.M., Amorim, M.J. (2016) Effects of ivermectin on Danio rerio: a multiple endpoint approach: behaviour, weight and subcellular markers. Ecotoxicology (London, England). 25(3):491-9
Azevedo, S.L., Ribeiro, F., Jurkschat, K., Soares, A.M., Loureiro, S. (2016) Co-exposure of ZnO nanoparticles and UV radiation to Daphnia magna and Danio rerio: Combined effects rather than protection. Environmental toxicology and chemistry. 35(2):458-67
Faria, M., Garcia-Reyero, N., Padrós, F., Babin, P.J., Sebastián, D., Cachot, J., Prats, E., Arick, M., Rial, E., Knoll-Gellida, A., Mathieu, G., Le Bihanic, F., Lynn Escalon, B., Zorzano, A., Soares, A.M., Raldúa, D. (2016) Corrigendum: Zebrafish Models for Human Acute Organophosphorus Poisoning. Scientific Reports. 6:17244
Andrade, T.S., Henriques, J.F., Almeida, A.R., Machado, A.L., Koba, O., Giang, P.T., Soares, A.M., Domingues, I. (2016) Carbendazim exposure induces developmental, biochemical and behavioural disturbance in zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 170:390-9
Henriques, J.F., Almeida, A.R., Andrade, T., Koba, O., Golovko, O., Soares, A.M., Oliveira, M., Domingues, I. (2016) Effects of the lipid regulator drug gemfibrozil: A toxicological and behavioral perspective. Aquatic toxicology (Amsterdam, Netherlands). 170:355-64
Oliveira, J.M., Almeida, A.R., Pimentel, T., Andrade, T.S., Henriques, J.F., Soares, A.M., Loureiro, S., Gomes, N.C., Domingues, I. (2016) Effect of chemical stress and ultraviolet radiation in the bacterial communities of zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 208(Pt B):626-36
Soares, A.R., Fernandes, N., Reverendo, M., Araújo, H.R., Oliveira, J.L., Moura, G.M., Santos, M.A. (2015) Conserved and highly expressed tRNA derived fragments in zebrafish. BMC Molecular Biology. 16:22
Faria, M., Garcia-Reyero, N., Padrós, F., Babin, P.J., Sebastián, D., Cachot, J., Prats, E., Arick Ii, M., Rial, E., Knoll-Gellida, A., Mathieu, G., Le Bihanic, F., Escalon, B.L., Zorzano, A., Soares, A.M., Raldúa, D. (2015) Zebrafish Models for Human Acute Organophosphorus Poisoning. Scientific Reports. 5:15591
Faria, M., Navas, J.M., Soares, A.M.V.M., Barata, C. (2015) Corrigendum to "Oxidative stress effects of titanium dioxide nanoparticle aggregates in zebrafish" [Sci. Total Environ. Volumes 470-471, 1 February 2014, Pages 379-389]. The Science of the total environment. 512-513:686
Monteiro, M.S., Pavlaki, M., Faustino, A., Rêma, A., Franchi, M., Gediel, L., Loureiro, S., Domingues, I., Rendón von Osten, J., Mortágua Velho Maia Soares, A. (2015) Endocrine disruption effects of p,p'-DDE on juvenile zebrafish. Journal of applied toxicology : JAT. 35(3):253-60
Oliveira, E., Casado, M., Faria, M., Soares, A.M., Navas, J.M., Barata, C., and Piña, B. (2014) Transcriptomic response of zebrafish embryos to polyaminoamine (PAMAM) dendrimers. Nanotoxicology. 8:92-9
Faria, M., Navas, J.M., Soares, A.M., and Barata, C. (2014) Oxidative stress effects of titanium dioxide nanoparticle aggregates in zebrafish embryos. The Science of the total environment. 470-471C:379-389
Reverendo, M., Soares, A.R., Pereira, P.M., Carreto, L., Ferreira, V., Gatti, E., Pierre, P., Moura, G.R., Santos, M.A. (2014) TRNA mutations that affect decoding fidelity deregulate development and the proteostasis network in zebrafish. RNA Biology. 11(9):1199-213
Ribeiro, F., Gallego-Urrea, J.A., Jurkschat, K., Crossley, A., Hassellöv, M., Taylor, C., Soares, A.M., and Loureiro, S. (2014) Silver nanoparticles and silver nitrate induce high toxicity to Pseudokirchneriella subcapitata, Daphnia magna and Danio rerio. The Science of the total environment. 466-467C:232-241
Oliveira, E., Casado, M., Raldúa, D., Soares, A., Barata, C., and Piña, B. (2013) Retinoic acid receptors' expression and function during zebrafish early development. The Journal of steroid biochemistry and molecular biology. 138:143-51
Oliveira, R., McDonough, S., Ladewig, J.C., Soares, A.M., Nogueira, A.J., and Domingues, I. (2013) Effects of oxytetracycline and amoxicillin on development and biomarkers activities of zebrafish (Danio rerio). Environmental Toxicology and Pharmacology. 36(3):903-912
Pérez, J., Domingues, I., Monteiro, M., Soares, A.M., and Loureiro, S. (2013) Synergistic effects caused by atrazine and terbuthylazine on chlorpyrifos toxicity to early-life stages of the zebrafish Danio rerio. Environmental science and pollution research international. 20(7):4671-80
Domingues, I., Oliveira, R., Musso, C., Cardoso, M., Soares, A.M., and Loureiro, S. (2013) Prochloraz effects on biomarkers activity in zebrafish early life stages and adults. Environmental toxicology. 28(3):155-163
Soares, J., Castro, L.F., Reis-Henriques, M.A., Monteiro, N.M., and Santos, M.M. (2012) Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways. Ecotoxicology (London, England). 21(5):1513-1522
Soares, A.R., Pereira, P.M., Ferreira, V., Reverendo, M., Simões, J., Bezerra, A.R., Moura, G.R., and Santos, M.A. (2012) Ethanol Exposure Induces Upregulation of Specific MicroRNAs in Zebrafish Embryos. Toxicological sciences : an official journal of the Society of Toxicology. 127(1):18-28
Castro, L.F., Lopes-Marques, M., Wilson, J.M., Rocha, E., Reis-Henriques, M.A., Santos, M.M., and Cunha, I. (2012) A novel Acetyl-CoA synthetase short-chain subfamily member 1 (Acss1) gene indicates a dynamic history of paralogue retention and loss in vertebrates. Gene. 497(2):249-255
Soares, A.R., Reverendo, M., Pereira, P.M., Nivelles, O., Pendeville, H., Bezerra, A.R., Moura, G.R., Struman, I., and Santos, M.A. (2012) Dre-miR-2188 Targets Nrp2a and Mediates Proper Intersegmental Vessel Development in Zebrafish Embryos. PLoS One. 7(6):e39417
Coelho, S., Oliveira, R., Pereira, S., Musso, C., Domingues, I., Bhujel, R.C., Soares, A.M., and Nogueira, A.J. (2011) Assessing lethal and sub-lethal effects of trichlorfon on different trophic levels. Aquatic toxicology (Amsterdam, Netherlands). 103(3-4):191-198
Domingues, I., Oliveira, R., Lourenço, J., Grisolia, C.K., Mendo, S., and Soares, A.M. (2010) Biomarkers as a tool to assess effects of chromium (VI): Comparison of responses in zebrafish early life stages and adults. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 152(3):338-345
Oliveira, R., Domingues, I., Koppe Grisolia, C., and Soares, A.M. (2009) Effects of triclosan on zebrafish early-life stages and adults. Environmental science and pollution research international. 16(6):679-688
Soares, A.R., Pereira, P.M., Santos, B., Egas, C., Gomes, A.C., Arrais, J., Oliveira, J.L., Moura, G.R., and Santos, M.A. (2009) Parallel DNA pyrosequencing unveils new zebrafish microRNAs. BMC Genomics. 10:195
Grisolia, C.K., Oliveira, R., Domingues, I., Oliveira-Filho, E.C., Monerat, R.G., and Soares, A.M. (2009) Genotoxic evaluation of different delta-endotoxins from Bacillus thuringiensis on zebrafish adults and development in early life stages. Mutation research. 672(2):119-123
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