ZFIN Lab: Neumann Lab, EMBL

ZFIN ID: ZDB-LAB-050818-1

Neumann Lab, EMBL

PI/Director:	Neumann, Carl J.
Contact Person:	Neumann, Carl J.
URL:
Address:	Developmental Biology Programme European Molecular Biology Laboratory (EMBL Heidelberg) Meyerhofstrasse 1 D-69117 Heidelberg GERMANY
Country:	Germany
Phone:	+49 6221 387186
Fax:	+49 6221 387166
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Gilmour, Darren Post-Doc

Rau, Marlene J. Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Möller, K., Brambach, M., Villani, A., Gallo, E., Gilmour, D., Peri, F. (2022) A role for the centrosome in regulating the rate of neuronal efferocytosis by microglia in vivo. eLIFE. 11:

Hachimi, M., Grabowski, C., Campanario, S., Herranz, G., Baonza, G., Serrador, J.M., Gomez-Lopez, S., Barea, M.D., Bosch-Fortea, M., Gilmour, D., Bagnat, M., Rodriguez-Fraticelli, A.E., Martin-Belmonte, F. (2020) Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis. Current biology : CB. 31(4):696-706.e9

Hartmann, J., Wong, M., Gallo, E., Gilmour, D. (2020) An image-based data-driven analysis of cellular architecture in a developing tissue. eLIFE. 9:

Wong, M., Newton, L.R., Hartmann, J., Hennrich, M.L., Wachsmuth, M., Ronchi, P., Guzmán-Herrera, A., Schwab, Y., Gavin, A.C., Gilmour, D. (2020) Dynamic Buffering of Extracellular Chemokine by a Dedicated Scavenger Pathway Enables Robust Adaptation during Directed Tissue Migration. Developmental Cell. 52(4):492-508.e10

Barry, J.D., Donà, E., Gilmour, D., Huber, W. (2016) TimerQuant: A modelling approach to tandem fluorescent timer design and data interpretation for measuring protein turnover in embryos. Development (Cambridge, England). 143(1):174-9

Durdu, S., Iskar, M., Revenu, C., Schieber, N., Kunze, A., Bork, P., Schwab, Y., Gilmour, D. (2014) Luminal signalling links cell communication to tissue architecture during organogenesis. Nature. 515(7525):120-4

Mazaheri, F., Breus, O., Durdu, S., Haas, P., Wittbrodt, J., Gilmour, D., Peri, F. (2014) Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia. Nature communications. 5:4046

Revenu, C., Streichan, S., Donà, E., Lecaudey, V., Hufnagel, L., Gilmour, D. (2014) Quantitative cell polarity imaging defines leader-to-follower transitions during collective migration and the key role of microtubule-dependent adherens junction formation. Development (Cambridge, England). 141:1282-91

Donà, E., Barry, J.D., Valentin, G., Quirin, C., Khmelinskii, A., Kunze, A., Durdu, S., Newton, L.R., Fernandez-Minan, A., Huber, W., Knop, M., and Gilmour, D. (2013) Directional tissue migration through a self-generated chemokine gradient. Nature. 503(7475):285-9

Streichan, S.J., Valentin, G., Gilmour, D., and Hufnagel, L. (2011) Collective cell migration guided by dynamically maintained gradients. Physical Biology. 8(4):045004

Rojas-Muñoz, A., Rajadhyksha, S., Gilmour, D., van Bebber, F., Antos, C., Rodríguez Esteban, C., Nüsslein-Volhard, C., and Izpisúa Belmonte, J.C. (2009) ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration. Developmental Biology. 327(1):177-190

Liu, Y.H., Jakobsen, J.S., Valentin, G., Amarantos, I., Gilmour, D.T., and Furlong, E.E. (2009) A Systematic Analysis of Tinman Function Reveals Eya and JAK-STAT Signaling as Essential Regulators of Muscle Development. Developmental Cell. 16(2):280-291

Prykhozhij, S.V., and Neumann, C.J. (2008) Distinct roles of Shh and Fgf signaling in regulating cell proliferation during zebrafish pectoral fin development. BMC Developmental Biology. 8(1):91

Lecaudey, V., Cakan-Akdogan, G., Norton, W.H., and Gilmour, D. (2008) Dynamic Fgf signaling couples morphogenesis and migration in the zebrafish lateral line primordium. Development (Cambridge, England). 135(16):2695-2705

Pouthas, F., Girard, P., Lecaudey, V., Ly, T.B., Gilmour, D., Boulin, C., Pepperkok, R., and Reynaud, E.G. (2008) In migrating cells, the Golgi complex and the position of the centrosome depend on geometrical constraints of the substratum. Journal of Cell Science. 121(Pt 14):2406-2414

Fischer, S., Prykhozhij, S., Rau, M.J., and Neumann, C.J. (2007) Mutation of Zebrafish caf-1b Results in S Phase Arrest, Defective Differentiation, and p53-Mediated Apoptosis During Organogenesis. Cell cycle (Georgetown, Tex.). 6(23):2962-2969

Manfroid, I., Delporte, F., Baudhuin, A., Motte, P., Neumann, C.J., Voz, M.L., Martial, J.A., and Peers, B. (2007) Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development. Development (Cambridge, England). 134(22):4011-4021

Valentin, G., Haas, P., and Gilmour, D. (2007) The chemokine SDF1a coordinates tissue migration through the spatially restricted activation of Cxcr7 and Cxcr4b. Current biology : CB. 17(12):1026-1031

Dickmeis, T., Lahiri, K., Nica, G., Vallone, D., Santoriello, C., Neumann, C.J., Hammerschmidt, M., and Foulkes, N.S. (2007) Glucocorticoids Play a Key Role in Circadian Cell Cycle Rhythms. PLoS Biology. 5(4):e78

Dong, P.D., Munson, C.A., Norton, W., Crosnier, C., Pan, X., Gong, Z., Neumann, C.J., and Stainier, D.Y. (2007) Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nature Genetics. 39(3):397-402

Mercader, N., Fischer, S., and Neumann, C.J. (2006) Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction. Development (Cambridge, England). 133(15):2805-2815

Rau, M.J., Fischer, S., and Neumann, C.J. (2006) Zebrafish Trap230/Med12 is required as a coactivator for Sox9-dependent neural crest, cartilage and ear development. Developmental Biology. 296(1):83-93

Haas, P., and Gilmour, D. (2006) Chemokine signaling mediates self-organizing tissue migration in the zebrafish lateral line. Developmental Cell. 10(5):673-680

Norton, W.H., Ledin, J., Grandel, H., and Neumann, C.J. (2005) HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development. Development (Cambridge, England). 132(22):4963-4973

Stadler, J.A., Shkumatava, A., Norton, W.H., Rau, M.J., Geisler, R., Fischer, S., and Neumann, C.J. (2005) Histone deacetylase 1 is required for cell cycle exit and differentiation in the zebrafish retina. Developmental Dynamics : an official publication of the American Association of Anatomists. 233(3):883-889

Shkumatava, A., and Neumann, C.J. (2005) Shh directs cell-cycle exit by activating p57Kip2 in the zebrafish retina. EMBO reports. 6(6):563-569

Norton, W.H., Mangoli, M., Lele, Z., Pogoda, H.M., Diamond, B., Mercurio, S., Russell, C., Teraoka, H., Stickney, H.L., Rauch, G.J., Heisenberg, C.P., Houart, C., Schilling, T.F., Frohnhoefer, H.G., Rastegar, S., Neumann, C.J., Gardiner, R.M., Strähle, U., Geisler, R., Rees, M., Talbot, W.S., and Wilson, S.W. (2005) Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones. Development (Cambridge, England). 132(4):645-658

Rau, M.J. (2005) Zebrafish Trap230/Med12 is required for Sox9 activity and limb induction. Ph.D. Thesis.

Shkumatava, A., Fischer, S., Müller, F., Strähle, U., and Neumann, C.J. (2004) Sonic hedgehog, secreted by amacrine cells, acts as a short-range signal to direct differentiation and lamination in the zebrafish retina. Development (Cambridge, England). 131(16):3849-3858

Gilmour, D., Knaut, H., Maischein, H.M., and Nüsslein-Volhard, C. (2004) Towing of sensory axons by their migrating target cells in vivo. Nature Neuroscience. 7(5):491-492

Stadler, J.A., Shkumatava, A., and Neumann, C.J. (2004) The role of hedgehog signaling in the development of the zebrafish visual system. Developmental neuroscience. 26(5-6):346-351

Fischer, S., Draper, B.W., and Neumann, C.J. (2003) The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation. Development (Cambridge, England). 130(15):3515-3524

Concha, M.L., Russell, C., Regan, J.C., Tawk, M., Sidi, S., Gilmour, D.T., Kapsimali, M., Sumoy, L., Goldstone, K., Amaya, E., Kimelman, D., Nicolson, T., Gründer, S., Gomperts, M., Clarke, J.D.W., and Wilson, S.W. (2003) Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron. 39(3):423-438

Albert, S., Müller, F., Fischer, N., Biellmann, D., Neumann, C., Blader, P., and Strähle, U. (2003) Cyclops-independent floor plate differentiation in zebrafish embryos. Developmental Dynamics : an official publication of the American Association of Anatomists. 226(1):59-66

Neumann, C.J. (2002) Vertebrate development: a view from the zebrafish. Seminars in cell & developmental biology. 13(6):469

Gilmour, D.T., Maischein, H.M., Nüsslein-Volhard, C. (2002) Migration and function of a glial subtype in the vertebrate peripheral nervous system. Neuron. 34(4):577-588

Neumann, C.J. (2001) Pattern formation in the zebrafish retina. Seminars in cell & developmental biology. 12(6):485-490

Neumann, C.J. and Nüsslein-Volhard, C. (2000) Patterning of the zebrafish retina by a wave of sonic hedgehog activity. Science (New York, N.Y.). 289(5487):2137-2139

Neumann, C.J., Grandel, H., Gaffield, W., Schulte-Merker, S., Nüsslein-Volhard, C. (1999) Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity. Development (Cambridge, England). 126(21):4817-4826

Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89