ZFIN ID: ZDB-LAB-030909-2
Poss Lab
PI/Director: Poss, Kenneth D.
Contact Person: Poss, Kenneth D.
Email: kenneth.poss@duke.edu
URL: http://sites.duke.edu/posslab/
Address: Duke Regeneration Center Department of Cell Biology, Box 3709 Duke University Medical Center Durham, NC 27710 USA
Country: United States
Phone: (919) 681-8457
Fax: (919) 684-5481
Line Designation: pd

Show first 50 of 236 genomic features

Modeling disease and regeneration in zebrafish.

Brown, David A. MD/Veterinarian Ando, Kazunori Post-Doc Bangru, Sushant Post-Doc
Furusho, Taisuke Post-Doc Gillotay, Pierre Post-Doc Pronobis, Mira Post-Doc
Ramkumar, Nitya Post-Doc Rich, Ashley Post-Doc Shen, Jingwen Post-Doc
Slota, Leslie Post-Doc Sun, Fei Post-Doc Wolfson, David Post-Doc
Becker, Clay Graduate Student Butt, Faraz Ahmed Graduate Student Ou, Jianhong Research Staff
Oonk, Kelsey Technical Staff Jackson, Amy Administrative Staff

Ando, K., Ou, J., Thompson, J.D., Welsby, J., Bangru, S., Shen, J., Wei, X., Diao, Y., Poss, K.D. (2024) A screen for regeneration-associated silencer regulatory elements in zebrafish. Developmental Cell. 59(5):676-691.e5
Zlatanova, I., Sun, F., Wu, R.S., Chen, X., Lau, B.H., Colombier, P., Sinha, T., Celona, B., Xu, S.M., Materna, S.C., Huang, G.N., Black, B.L. (2023) An injury-responsive mmp14b enhancer is required for heart regeneration. Science advances. 9:eadh5313eadh5313
Becker, C.J., Cigliola, V., Gillotay, P., Rich, A., De Simone, A., Han, Y., Di Talia, S., Poss, K.D. (2023) In toto imaging of glial JNK signaling during larval zebrafish spinal cord regeneration. Development (Cambridge, England). 150(24):
Rao, A., Lyu, B., Jahan, I., Lubertozzi, A., Zhou, G., Tedeschi, F., Jankowsky, E., Kang, J., Carstens, B., Poss, K.D., Baskin, K., Goldman, J.A. (2023) The translation initiation factor homolog eif4e1c regulates cardiomyocyte metabolism and proliferation during heart regeneration. Development (Cambridge, England). 150(20):
Cigliola, V., Shoffner, A., Lee, N., Ou, J., Gonzalez, T.J., Hoque, J., Becker, C.J., Han, Y., Shen, G., Faw, T.D., Abd-El-Barr, M.M., Varghese, S., Asokan, A., Poss, K.D. (2023) Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer. Nature communications. 14:48574857
Haerlingen, B., Opitz, R., Vandernoot, I., Molinaro, A., Shankar, M.P., Gillotay, P., Trubiroha, A., Costagliola, S. (2023) Mesodermal FGF and BMP govern the sequential stages of zebrafish thyroid specification. Development (Cambridge, England). 150(10):
Zhou, L., McAdow, A.R., Yamada, H., Burris, B., Klatt Shaw, D., Oonk, K., Poss, K.D., Mokalled, M.H. (2023) Progenitor-derived glia are required for spinal cord regeneration in zebrafish. Development (Cambridge, England). 150(10):
Yan, R., Cigliola, V., Oonk, K.A., Petrover, Z., DeLuca, S., Wolfson, D.W., Vekstein, A., Mendiola, M.A., Devlin, G., Bishawi, M., Gemberling, M.P., Sinha, T., Sargent, M.A., York, A.J., Shakked, A., DeBenedittis, P., Wendell, D.C., Ou, J., Kang, J., Goldman, J.A., Baht, G.S., Karra, R., Williams, A.R., Bowles, D.E., Asokan, A., Tzahor, E., Gersbach, C.A., Molkentin, J.D., Bursac, N., Black, B.L., Poss, K.D. (2022) An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair. Cell Stem Cell. 30(1):96-111.e6
Osorio-Méndez, D., Miller, A., Begeman, I.J., Kurth, A., Hagle, R., Rolph, D., Dickson, A.L., Chen, C.H., Halloran, M., Poss, K.D., Kang, J. (2022) Voltage-gated sodium channel scn8a is required for innervation and regeneration of amputated adult zebrafish fins. Proceedings of the National Academy of Sciences of the United States of America. 119:e2200342119
Sun, J., Peterson, E.A., Wang, A.Z., Ou, J., Smith, K.E., Poss, K.D., Wang, J. (2022) hapln1 Defines an Epicardial Cell Subpopulation Required for Cardiomyocyte Expansion During Heart Morphogenesis and Regeneration. Circulation. 146(1):48-63
Das, R.N., Tevet, Y., Safriel, S., Han, Y., Moshe, N., Lambiase, G., Bassi, I., Nicenboim, J., Brückner, M., Hirsch, D., Eilam-Altstadter, R., Herzog, W., Avraham, R., Poss, K.D., Yaniv, K. (2022) Generation of specialized blood vessels via lymphatic transdifferentiation. Nature. 606(7914):570-575
Sun, F., Ou, J., Shoffner, A.R., Luan, Y., Yang, H., Song, L., Safi, A., Cao, J., Yue, F., Crawford, G.E., Poss, K.D. (2022) Enhancer selection dictates gene expression responses in remote organs during tissue regeneration. Nature cell biology. 24(5):685-696
Cao, Y., Xia, Y., Balowski, J.J., Ou, J., Song, L., Safi, A., Curtis, T., Crawford, G.E., Poss, K.D., Cao, J. (2022) Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration. Development (Cambridge, England). 149(4)
Peng, X., Lai, K.S., She, P., Kang, J., Wang, T., Li, G., Zhou, Y., Sun, J., Jin, D., Xu, X., Liao, L., Liu, J., Lee, E., Poss, K.D., Zhong, T.P. (2022) Corrigendum to 'Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration'. Journal of molecular cell biology. 13:921
Tseng, T.L., Wang, Y.T., Tsao, C.Y., Ke, Y.T., Lee, Y.C., Hsu, H.J., Poss, K.D., Chen, C.H. (2021) The RNA helicase Ddx52 functions as a growth switch in juvenile zebrafish. Development (Cambridge, England). 148(15):
Hayden, L.D., Poss, K.D., De Simone, A., Di Talia, S. (2021) Mathematical modeling of Erk activity waves in regenerating zebrafish scales. Biophysical journal. 120(19):4287-4297
Pronobis, M.I., Zheng, S., Singh, S.P., Goldman, J.A., Poss, K.D. (2021) In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration. eLIFE. 10:
De Simone, A., Evanitsky, M.N., Hayden, L., Cox, B.D., Wang, J., Tornini, V.A., Ou, J., Chao, A., Poss, K.D., Di Talia, S. (2021) Control of osteoblast regeneration by a train of Erk activity waves. Nature. 590(7844):129-133
Sun, F., Shoffner, A.R., Poss, K.D. (2021) A Genetic Cardiomyocyte Ablation Model for the Study of Heart Regeneration in Zebrafish. Methods in molecular biology (Clifton, N.J.). 2158:71-80
Ye, L., Bae, M., Cassilly, C.D., Jabba, S.V., Thorpe, D.W., Martin, A.M., Lu, H.Y., Wang, J., Thompson, J.D., Lickwar, C.R., Poss, K.D., Keating, D.J., Jordt, S.E., Clardy, J., Liddle, R.A., Rawls, J.F. (2020) Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways. Cell Host & Microbe. 29(2):179-196.e9
Mukherjee, D., Wagh, G., Mokalled, M.H., Kontarakis, Z., Dickson, A.L., Rayrikar, A., Günther, S., Poss, K.D., Stainier, D.Y.R., Patra, C. (2020) Ccn2a/Ctgfa is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish. Development (Cambridge, England). 148(2):
Gillotay, P., Shankar, M., Haerlingen, B., Sema Elif, E., Pozo-Morales, M., Garteizgogeascoa, I., Reinhardt, S., Kränkel, A., Bläsche, J., Petzold, A., Ninov, N., Kesavan, G., Lange, C., Brand, M., Lefort, A., Libert, F., Detours, V., Costagliola, S., Singh, S.P. (2020) Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland. EMBO reports. 21(12):e50612
Chen, A., Han, Y., Poss, K.D. (2020) Regulation of Zebrafish Fin Regeneration by Vitamin D Signaling. Developmental Dynamics : an official publication of the American Association of Anatomists. 250(9):1330-1339
Oonk, K.A., Bienvenu, L.B., Sickler, P.S., Martin, C., Nickoloff-Bybel, E., Volk, A.M., Weiser, D.C., Walsh, S. (2020) Zebrafish Trak proteins 1a and 2 localize to the mitochondria. microPublication. Biology. 2020:
Peng, X., Lai, K.S., She, P., Kang, J., Wang, T., Li, G., Zhou, Y., Sun, J., Jin, D., Xu, X., Liao, L., Liu, J., Lee, E., Poss, K.D., Zhong, T.P. (2020) Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration. Journal of molecular cell biology. 13(1):41-58
Ramkumar, N., Sun, F., Poss, K.D. (2020) Tissue Repair: A Tendon-see to Regenerate. Current biology : CB. 30:R1001-R1003
Shoffner, A., Cigliola, V., Lee, N., Ou, J., Poss, K.D. (2020) Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration. Cell Reports. 32:108089
Vandernoot, I., Haerlingen, B., Gillotay, P., Trubiroha, A., Janssens, V., Opitz, R., Costagliola, S. (2020) Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects. Thyroid : official journal of the American Thyroid Association. 31(3):420-438
Thompson, J.D., Ou, J., Lee, N., Shin, K., Cigliola, V., Song, L., Crawford, G.E., Kang, J., Poss, K.D. (2020) Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration. Development (Cambridge, England). 147(14):
Cigliola, V., Becker, C.J., Poss, K.D. (2020) Building bridges, not walls: spinal cord regeneration in zebrafish. Disease models & mechanisms. 13(5):
Pronobis, M.I., Poss, K.D. (2020) Signals for cardiomyocyte proliferation during zebrafish heart regeneration. Current opinion in physiology. 14:78-85
Wang, Z., Li, Y., Hou, B., Pronobis, M.I., Wang, M., Wang, Y., Cheng, G., Weng, W., Wang, Y., Tang, Y., Xu, X., Pan, R., Lin, F., Wang, N., Chen, Z., Wang, S., Ma, L.Z., Li, Y., Huang, D., Jiang, L., Wang, Z., Zeng, W., Zhang, Y., Du, X., Lin, Y., Li, Z., Xia, Q., Geng, J., Dai, H., Yu, Y., Zhao, X.D., Yuan, Z., Yan, J., Nie, Q., Zhang, X., Wang, K., Chen, F., Zhang, Q., Zhu, Y., Zheng, S., Poss, K.D., Tao, S.C., Meng, X. (2020) An array of 60,000 antibodies for proteome-scale antibody generation and target discovery. Science advances. 6:eaax2271
Honkoop, H., de Bakker, D.E., Aharonov, A., Kruse, F., Shakked, A., Nguyen, P.D., de Heus, C., Garric, L., Muraro, M.J., Shoffner, A., Tessadori, F., Peterson, J.C., Noort, W., Bertozzi, A., Weidinger, G., Posthuma, G., Grun, D., van der Laarse, W.J., Klumperman, J., Jaspers, R.T., Poss, K.D., van Oudenaarden, A., Tzahor, E., Bakkers, J. (2019) Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart. eLIFE. 8:
McDaniel, D.K., Ringel-Scaia, V.M., Morrison, H.A., Coutermarsh-Ott, S., Council-Troche, M., Angle, J.W., Perry, J.B., Davis, G., Leng, W., Minarchick, V., Yang, Y., Chen, B., Reece, S.W., Brown, D.A., Cecere, T.E., Brown, J.M., Gowdy, K.M., Hochella, M.F., Allen, I.C. (2019) Pulmonary Exposure to Magnéli Phase Titanium Suboxides Results in Significant Macrophage Abnormalities and Decreased Lung Function. Frontiers in immunology. 10:2714
Wang, Y.T., Tseng, T.L., Kuo, Y.C., Yu, J.K., Su, Y.H., Poss, K.D., Chen, C.H. (2019) Genetic Reprogramming of Positional Memory in a Regenerating Appendage. Current biology : CB. 29(24):4193-4207.e4
Marín-Juez, R., El-Sammak, H., Helker, C.S.M., Kamezaki, A., Mullapuli, S.T., Bibli, S.I., Foglia, M.J., Fleming, I., Poss, K.D., Stainier, D.Y.R. (2019) Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. Developmental Cell. 51:503-515.e4
Gancz, D., Raftrey, B.C., Perlmoter, G., Marín-Juez, R., Semo, J., Matsuoka, R.L., Karra, R., Raviv, H., Moshe, N., Addadi, Y., Golani, O., Poss, K.D., Red-Horse, K., Stainier, D.Y., Yaniv, K. (2019) Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration. eLIFE. 8:
Giusti, N., Gillotay, P., Trubiroha, A., Opitz, R., Dumont, J.E., Costagliola, S., De Deken, X. (2019) Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound. Molecular and Cellular Endocrinology. 500:110635
Wang, C., Gong, S., Liang, Z., Sun, Y., Cheng, R., Yang, B., Liu, Y., Yang, J., Sun, F. (2019) Ligand-Promoted Iridium-Catalyzed Transfer Hydrogenation of Terminal Alkynes with Ethanol and Its Application. ACS omega. 4:16045-16051
Haerlingen, B., Opitz, R., Vandernoot, I., Trubiroha, A., Gillotay, P., Giusti, N., Costagliola, S. (2019) Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development. Thyroid : official journal of the American Thyroid Association. 29(11):1683-1703
Han, Y., Chen, A., Umansky, K.B., Oonk, K.A., Choi, W.Y., Dickson, A.L., Ou, J., Cigliola, V., Yifa, O., Cao, J., Tornini, V.A., Cox, B.D., Tzahor, E., Poss, K.D. (2019) Vitamin D Stimulates Cardiomyocyte Proliferation and Controls Organ Size and Regeneration in Zebrafish. Developmental Cell. 48(6):853-863.e5
Cox, B.D., De Simone, A., Tornini, V.A., Singh, S.P., Di Talia, S., Poss, K.D. (2018) In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone. Current biology : CB. 28(24):3937-3947.e4
Mokalled, M.H., Poss, K.D. (2018) A Regeneration Toolkit. Developmental Cell. 47:267-280
Walton, E.M., Cronan, M.R., Cambier, C.J., Rossi, A., Marass, M., Foglia, M.D., Brewer, W.J., Poss, K.D., Stainier, D.Y.R., Bertozzi, C.R., Tobin, D.M. (2018) Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling. Cell Host & Microbe. 24:514-525.e6
Karra, R., Foglia, M.J., Choi, W.Y., Belliveau, C., DeBenedittis, P., Poss, K.D. (2018) Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 115(35):8805-8810
Cao, J., Poss, K.D. (2018) The epicardium as a hub for heart regeneration. Nature reviews. Cardiology. 15(10):631-647
Trubiroha, A., Gillotay, P., Giusti, N., Gacquer, D., Libert, F., Lefort, A., Haerlingen, B., De Deken, X., Opitz, R., Costagliola, S. (2018) A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function. Scientific Reports. 8:5647
Shibata, E., Ando, K., Murase, E., Kawakami, A. (2018) Heterogeneous fates and dynamic rearrangement of regenerative epidermis-derived cells during zebrafish fin regeneration. Development (Cambridge, England). 145(8)
Wopat, S., Bagwell, J., Sumigray, K.D., Dickson, A.L., Huitema, L.F.A., Poss, K.D., Schulte-Merker, S., Bagnat, M. (2018) Spine Patterning Is Guided by Segmentation of the Notochord Sheath. Cell Reports. 22:2026-2038
Chen, C.H., Poss, K.D. (2017) Regeneration Genetics. Annual review of genetics. 51:63-82
Ando, K., Shibata, E., Hans, S., Brand, M., Kawakami, A. (2017) Osteoblast Production by Reserved Progenitor Cells in Zebrafish Bone Regeneration and Maintenance. Developmental Cell. 43(5):643-650.e3
Cao, J., Wang, J., Jackman, C.P., Cox, A.H., Trembley, M.A., Balowski, J.J., Cox, B.D., De Simone, A., Dickson, A.L., Di Talia, S., Small, E.M., Kiehart, D.P., Bursac, N., Poss, K.D. (2017) Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue. Developmental Cell. 42:600-615.e4
Tornini, V.A., Thompson, J.D., Allen, R.L., Poss, K.D. (2017) Live fate-mapping of joint-associated fibroblasts visualizes expansion of cell contributions during zebrafish fin regeneration. Development (Cambridge, England). 144:2889-2895
Goldman, J.A., Kuzu, G., Lee, N., Karasik, J., Gemberling, M., Foglia, M.J., Karra, R., Dickson, A.L., Sun, F., Tolstorukov, M.Y., Poss, K.D. (2017) Resolving Heart Regeneration by Replacement Histone Profiling. Developmental Cell. 40:392-404.e5
Karra, R., Poss, K.D. (2017) Redirecting cardiac growth mechanisms for therapeutic regeneration. The Journal of Clinical Investigation. 127:427-436
Nichols, J.T., Blanco-Sánchez, B., Brooks, E.P., Parthasarathy, R., Dowd, J., Subramanian, A., Nachtrab, G., Poss, K.D., Schilling, T.F., Kimmel, C.B. (2016) Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca. Development (Cambridge, England). 143(23):4430-4440
Tornini, V.A., Puliafito, A., Slota, L.A., Thompson, J.D., Nachtrab, G., Kaushik, A.L., Kapsimali, M., Primo, L., Di Talia, S., Poss, K.D. (2016) Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration. Current biology : CB. 26(22):2981-2991
Mokalled, M.H., Patra, C., Dickson, A.L., Endo, T., Stainier, D.Y., Poss, K.D. (2016) Injury-induced ctgfa directs glial bridging and spinal cord regeneration in zebrafish. Science (New York, N.Y.). 354:630-634
Foglia, M.J., Cao, J., Tornini, V.A., Poss, K.D. (2016) Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium. Development (Cambridge, England). 143(10):1688-96
Cao, J., Poss, K.D. (2016) Explant culture of adult zebrafish hearts for epicardial regeneration studies. Nature Protocols. 11:872-881
Kang, J., Hu, J., Karra, R., Dickson, A.L., Tornini, V.A., Nachtrab, G., Gemberling, M., Goldman, J.A., Black, B.L., Poss, K.D. (2016) Modulation of tissue repair by regeneration enhancer elements. Nature. 532(7598):201-6
Chen, C.H., Puliafito, A., Cox, B.D., Primo, L., Fang, Y., Di Talia, S., Poss, K.D. (2016) Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish. Developmental Cell. 36:668-80
Foglia, M.J., Poss, K.D. (2016) Building and re-building the heart by cardiomyocyte proliferation. Development (Cambridge, England). 143:729-40
Cao, J., Navis, A., Cox, B.D., Dickson, A.L., Gemberling, M., Karra, R., Bagnat, M., Poss, K.D. (2016) Single epicardial cell transcriptome sequencing identifies Caveolin-1 as an essential factor in zebrafish heart regeneration. Development (Cambridge, England). 143(2):232-43
Wang, J., Poss, K.D. (2016) Methodologies for Inducing Cardiac Injury and Assaying Regeneration in Adult Zebrafish. Methods in molecular biology (Clifton, N.J.). 1451:225-35
Karra, R., Knecht, A.K., Kikuchi, K., Poss, K.D. (2015) Myocardial NF-κB activation is essential for zebrafish heart regeneration. Proceedings of the National Academy of Sciences of the United States of America. 112(43):13255-60
Chen, C.H., Merriman, A.F., Savage, J., Willer, J., Wahlig, T., Katsanis, N., Yin, V.P., Poss, K.D. (2015) Transient laminin beta 1a Induction Defines the Wound Epidermis during Zebrafish Fin Regeneration. PLoS Genetics. 11:e1005437
Mahmoud, A.I., O'Meara, C.C., Gemberling, M., Zhao, L., Bryant, D.M., Zheng, R., Gannon, J.B., Cai, L., Choi, W.Y., Egnaczyk, G.F., Burns, C.E., Burns, C.G., MacRae, C.A., Poss, K.D., Lee, R.T. (2015) Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration. Developmental Cell. 34(4):387-99
Nagelberg, D., Wang, J., Su, R., Torres-Vazquez, J., Targoff, K.L., Poss, K.D., Knaut, H. (2015) Origin, specification and plasticity of the great vessels of the heart.. Current biology : CB. 25:2099-2110
Wang, F., Huang, G.D., Tian, H., Zhong, Y.B., Shi, H.J., Li, Z., Zhang, X.S., Wang, H., Sun, F. (2015) Point mutations in KAL1 and the mitochondrial gene MT-tRNA(cys) synergize to produce Kallmann syndrome phenotype. Scientific Reports. 5:13050
Gemberling, M., Karra, R., Dickson, A.L., Poss, K.D. (2015) Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish. eLIFE. 4
Schindler, Y.L., Garske, K.M., Wang, J., Firulli, B.A., Firulli, A.B., Poss, K.D., Yelon, D. (2014) Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration. Development (Cambridge, England). 141(16):3112-22
Chen, C.H., Durand, E., Wang, J., Zon, L.I., and Poss, K.D. (2013) zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England). 140(24):4988-97
Gemberling, M., Bailey, T.J., Hyde, D.R., and Poss, K.D. (2013) The zebrafish as a model for complex tissue regeneration. Trends in genetics : TIG. 29(11):611-20
Wang, J., Karra, R., Dickson, A.L., and Poss, K.D. (2013) Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration. Developmental Biology. 382(2):427-435
Kang, J., Nachtrab, G., and Poss, K.D. (2013) Local dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins. Developmental Cell. 27(1):19-31
Johnson, A.N., Mokalled, M.H., Valera, J.M., Poss, K.D., and Olson, E.N. (2013) Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi. Development (Cambridge, England). 140(17):3645-3656
Nachtrab, G., Kikuchi, K., Tornini, V.A., and Poss, K.D. (2013) Transcriptional components of anteroposterior positional information during zebrafish fin regeneration. Development (Cambridge, England). 140(18):3754-3764
Fang, Y., Gupta, V., Karra, R., Holdway, J.E., Kikuchi, K., and Poss, K.D. (2013) Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration. Proceedings of the National Academy of Sciences of the United States of America. 110(33):13416-13421
Gupta, V., Gemberling, M., Karra, R., Rosenfeld, G.E., Evans, T., and Poss, K.D. (2013) An Injury-Responsive Gata4 Program Shapes the Zebrafish Cardiac Ventricle. Current biology : CB. 23(13):1221-7
Le, X., Pugach, E.K., Hettmer, S., Storer, N.Y., Liu, J., Wills, A.A., Dibiase, A., Chen, E.Y., Ignatius, M.S., Poss, K.D., Wagers, A.J., Langenau, D.M., and Zon, L.I. (2013) A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England). 140(11):2354-64
Guner-Ataman, B., Paffett-Lugassy, N., Adams, M.S., Nevis, K.R., Jahangiri, L., Obregon, P., Kikuchi, K., Poss, K.D., Burns, C.E., and Burns, C.G. (2013) Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function. Development (Cambridge, England). 140(6):1353-1363
Choi, W.Y., Gemberling, M., Wang, J., Holdway, J.E., Shen, M.C., Karlstrom, R.O., and Poss, K.D. (2013) In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration. Development (Cambridge, England). 140(3):660-666
Yin, V.P., Lepilina, A., Smith, A., and Poss, K.D. (2012) Regulation of zebrafish heart regeneration by miR-133. Developmental Biology. 365(2):319-327
Gupta, V., and Poss, K.D. (2012) Clonally dominant cardiomyocytes direct heart morphogenesis. Nature. 484(7395):479-484
Singh, S.P., Holdway, J.E., and Poss, K.D. (2012) Regeneration of amputated zebrafish fin rays from de novo osteoblasts. Developmental Cell. 22(4):879-886
Choi, W.Y., and Poss, K.D. (2012) Cardiac regeneration. Current topics in developmental biology. 100:319-344
Kikuchi, K., and Poss, K.D. (2012) Cardiac regenerative capacity and mechanisms. Annual Review of Cell and Developmental Biology. 28:719-741
Nachtrab, G., Czerwinski, M., and Poss, K.D. (2011) Sexually Dimorphic Fin Regeneration in Zebrafish Controlled by Androgen/GSK3 Signaling. Current biology : CB. 21(22):1912-7
Qin, Z., Kidd, A.R., Thomas, J.L., Poss, K.D., Hyde, D.R., Raymond, P.A., and Thummel, R. (2011) FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish. Experimental Eye Research. 93(5):726-34
Wang, J., Panáková, D., Kikuchi, K., Holdway, J.E., Gemberling, M., Burris, J.S., Singh, S.P., Dickson, A.L., Lin, Y.F., Sabeh, M.K., Werdich, A.A., Yelon, D., MacRae, C.A., and Poss, K.D. (2011) The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion. Development (Cambridge, England). 138(16):3421-30
Kikuchi, K., Gupta, V., Wang, J., Holdway, J.E., Wills, A.A., Fang, Y., and Poss, K.D. (2011) tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration. Development (Cambridge, England). 138(14):2895-902
Shin, D., Lee, Y., Poss, K.D., and Stainier, D.Y. (2011) Restriction of hepatic competence by Fgf signaling. Development (Cambridge, England). 138(7):1339-1348
Kikuchi, K., Holdway, J.E., Major, R.J., Blum, N., Dahn, R.D., Begemann, G., and Poss, K.D. (2011) Retinoic Acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. Developmental Cell. 20(3):397-404
Liu, J., Bressan, M., Hassel, D., Huisken, J., Staudt, D., Kikuchi, K., Poss, K.D., Mikawa, T., and Stainier, D.Y. (2010) A dual role for ErbB2 signaling in cardiac trabeculation. Development (Cambridge, England). 137(22):3867-3875
Lee, Y., Nachtrab, G., Klinsawat, P.W., Hami, D., and Poss, K.D. (2010) Ras controls melanocyte expansion during zebrafish fin stripe regeneration. Disease models & mechanisms. 3(7-8):496-503
Yin, C., Kikuchi, K., Hochgreb, T., Poss, K.D., and Stainier, D.Y. (2010) Hand2 Regulates Extracellular Matrix Remodeling Essential for Gut-Looping Morphogenesis in Zebrafish. Developmental Cell. 18(6):973-984
Kikuchi, K., Holdway, J.E., Werdich, A.A., Anderson, R.M., Fang, Y., Egnaczyk, G.F., Evans, T., MacRae, C.A., Stainier, D.Y., and Poss, K.D. (2010) Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature. 464(7288):601-605
Gonzalez-Quevedo, R., Lee, Y., Poss, K.D., and Wilkinson, D.G. (2010) Neuronal Regulation of the Spatial Patterning of Neurogenesis. Developmental Cell. 18(1):136-147
Lee, Y., Hami, D., De Val, S., Kagermeier-Schenk, B., Wills, A.A., Black, B.L., Weidinger, G., and Poss, K.D. (2009) Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins. Developmental Biology. 331(2):270-280
Waxman, J.S., Keegan, B.R., Roberts, R.W., Poss, K.D., and Yelon, D. (2008) Hoxb5b acts downstream of retinoic Acid signaling in the forelimb field to restrict heart field potential in zebrafish. Developmental Cell. 15(6):923-934
Marques, S.R., Lee, Y., Poss, K.D., and Yelon, D. (2008) Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart. Developmental Biology. 321(2):397-406
Wills, A.A., Kidd Iii, A.R., Lepilina, A., and Poss, K.D. (2008) Fgfs control homeostatic regeneration in adult zebrafish fins. Development (Cambridge, England). 135(18):3063-3078
Yin, V.P., and Poss, K.D. (2008) New regulators of vertebrate appendage regeneration. Current opinion in genetics & development. 18(4):381-386
Yin, V.P., Thomson, J.M., Thummel, R., Hyde, D.R., Hammond, S.M., and Poss, K.D. (2008) Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. Genes & Development. 22(6):728-733
Wills, A.A., Holdway, J.E., Major, R.J., and Poss, K.D. (2008) Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish. Development (Cambridge, England). 135(1):183-192
Shin, D., Shin, C.H., Tucker, J., Ober, E.A., Rentzsch, F., Poss, K.D., Hammerschmidt, M., Mullins, M.C., and Stainier, D.Y. (2007) Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (Cambridge, England). 134(11):2041-2050
Nechiporuk, A., Linbo, T., Poss, K.D., and Raible, D.W. (2007) Specification of epibranchial placodes in zebrafish. Development (Cambridge, England). 134(3):611-623
Poss, K.D. (2007) Getting to the heart of regeneration in zebrafish. Seminars in cell & developmental biology. 18(1):36-45
Lepilina, A., Coon, A.N., Kikuchi, K., Holdway, J.E., Roberts, R.W., Burns, C.G., and Poss, K.D. (2006) A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration. Cell. 127(3):607-619
Lee, Y., Grill, S., Sanchez, A., Murphy-Ryan, M., Poss, K.D. (2005) Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration. Development (Cambridge, England). 132(23):5173-5183
Poss, K.D. (2004) A Zebrafish Model of Germ Cell Aneuploidy. Cell cycle (Georgetown, Tex.). 3(10):1225-1226
Poss, K.D., Nechiporuk, A., Stringer, K.F., Lee, C., and Keating, M.T. (2004) Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1. Genes & Development. 18(13):1527-1532
Traver, D., Paw, B.H., Poss, K.D., Penberthy, W.T., Lin, S., and Zon, L.I. (2003) Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature immunology. 4(12):1238-1246
Nechiporuk, A., Poss, K.D., Johnson, S.L., and Keating, M.T. (2003) Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration. Developmental Biology. 258(2):291-306
Poss, K.D., Keating, M.T., and Nechiporuk, A. (2003) Tales of regeneration in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 226(2):202-210
Gillette-Ferguson, I., Ferguson, D.G., Poss, K.D., and Moorman, S.J. (2003) Changes in gravitational force induce alterations in gene expression that can be monitored in the live, developing zebrafish heart. Advances in space research : the official journal of the Committee on Space Research (COSPAR). 32(8):1641-1646
Poss, K.D., Wilson, L.G., and Keating, M.T. (2002) Heart regeneration in zebrafish. Science (New York, N.Y.). 298(5601):2188-2190
Poss, K.D., Nechiporuk, A., Hillam, A.M., Johnson, S.L., and Keating, M.T. (2002) Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration. Development (Cambridge, England). 129(22):5141-5149
Poss, K.D., Shen, J.X., and Keating, M.T. (2000) Induction of lef1 during zebrafish fin regeneration. Developmental Dynamics : an official publication of the American Association of Anatomists. 219(2):282-286
Poss, K.D., Shen, J., Nechiporuk, A., McMahon, G., Thisse, B., Thisse, C., and Keating, M.T. (2000) Roles for Fgf signaling during zebrafish fin regeneration. Developmental Biology. 222(2):347-358