| Phenotype: | neural tube smoothened signaling pathway increased process quality, exacerbated |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | neural tube |
|---|---|
| Synonyms: | presumptive central nervous system |
| Definition: | Portion of tissue that is the cavity-containing primordium of the central nervous system, developing from the neural rod in the late segmentation period. |
| Ontology: | Anatomy Ontology [ZFA:0001135] |
| Name: | smoothened signaling pathway |
|---|---|
| Synonyms: | hedgehog signaling pathway, hh signaling pathway, hh signalling pathway, Shh signaling pathway, smoothened signalling pathway, Sonic hedgehog signaling pathway |
| Definition: | The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. |
| Ontology: | GO: Biological Process [GO:0007224] QuickGO AmiGO |
| Name: | increased process quality |
|---|---|
| Synonyms: | |
| Definition: | A quality of a process that has a value that is increased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002304] |
| Tag: | exacerbated |
|---|---|
| Definition: | This annotation denotes a significantly exaggerated phenotype resulting from an additional reagent or mutation. |