| Phenotype: | cranial nerve VIII synapse Ab1-gjd2a labeling absent, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | cranial nerve VIII |
|---|---|
| Synonyms: | auditory nerve, CN-VIII, cochleovestibular nerve, octaval nerve, statoacoustic nerve |
| Definition: | |
| Ontology: | Anatomy Ontology [ZFA:0000247] |
| Name: | synapse |
|---|---|
| Synonyms: | electrotonic synapse, mixed synapse, synaptic junction |
| Definition: | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
| Ontology: | GO: Cellular Component [GO:0045202] QuickGO AmiGO |
ANTIBODY LABELING:
EXPRESSION QUALITY:
| Name: | absent |
|---|---|
| Synonyms: | absence, absent from organism |
| Definition: | A quality denoting the lack of an entity. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000462] |