ZFIN Phenotype Statement: thymus hematopoietic multipotent progenitor cell myb expression increased amount, abnormal

Phenotype:	thymus hematopoietic multipotent progenitor cell myb expression increased amount, abnormal
Note:	This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality.

EXPRESSION ANATOMY:

Name:	thymus
Synonyms:
Definition:	Paired organ where maturation of T-lymphocytes occurs. The adult thymus located on the dorsomedial aspect of the branchial cavity above the third pharyngeal cartilage. The thymus undergoes a period of rapid growth beginning at about the third week and continuing for several more weeks. Accompanying this growth is a dramatic change in the shape of the thymus. It is ovoid initially and then starts to grow dorsally along the skull, forming a characteristic protrusion. During this growth period the adult pattern of rag1-positive cortex and rag1-negative medulla becomes established. The protrusions diminish with age and the thymus gradually shrinks; at two years, the thymus is again confined to the pharynx with minimal if any protrusion.
Ontology:	Anatomy Ontology [ZFA:0001078]

Name:	hematopoietic multipotent progenitor cell
Synonyms:	hemopoietic progenitor cell
Definition:	A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
Ontology:	Anatomy Ontology [ZFA:0009354]

EXPRESSED GENE:

Symbol:

Name:

v-myb avian myeloblastosis viral oncogene homolog

Previous Names:

c-myb, cmyb

Location:

Chr: 23 Mapping Details/Browsers

EXPRESSION QUALITY:

Name:	increased amount
Synonyms:	accessory, increased, increased number, present in greater numbers in organism, supernumerary
Definition:	An amount which is relatively high.
Ontology:	Phenotypic Quality Ontology [PATO:0000470]