| Phenotype: | hindbrain apoptotic process increased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | hindbrain |
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| Synonyms: | rhombencephalon |
| Definition: | The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata and thus these are not distinguished here. From Neuroanatomy of the Zebrafish Brain. |
| Ontology: | Anatomy Ontology [ZFA:0000029] |
| Name: | apoptotic process |
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| Synonyms: | apoptosis, apoptosis activator activity, apoptosis signaling, apoptotic cell death, apoptotic program, apoptotic programmed cell death, caspase-dependent programmed cell death, cell suicide, cellular suicide, commitment to apoptosis, induction of apoptosis, induction of apoptosis by p53, programmed cell death by apoptosis, signaling (initiator) caspase activity, type I programmed cell death |
| Definition: | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| Ontology: | GO: Biological Process [GO:0006915] QuickGO AmiGO |
| Name: | increased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is increased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002304] |