| Phenotype: | corneal epithelium desmosome decreased amount, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | corneal epithelium |
|---|---|
| Synonyms: | |
| Definition: | Portion of tissue comprised of four to six layers of nonkeratinized, stratified squamous cells and represents approximately 60% of the thickness of the cornea. |
| Ontology: | Anatomy Ontology [ZFA:0001683] |
| Name: | desmosome |
|---|---|
| Synonyms: | macula adherens, spot desmosome |
| Definition: | A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
| Ontology: | GO: Cellular Component [GO:0030057] QuickGO AmiGO |
| Name: | decreased amount |
|---|---|
| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |