| Phenotype: | retinal pigmented epithelium vacuole increased amount, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | retinal pigmented epithelium |
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| Synonyms: | pigmented epithelium, pigmented retina, pigmented retinal epithelium, PRE, RPE |
| Definition: | A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup. |
| Ontology: | Anatomy Ontology [ZFA:0000144] |
| Name: | vacuole |
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| Synonyms: | vacuolar carboxypeptidase Y |
| Definition: | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
| Ontology: | GO: Cellular Component [GO:0005773] QuickGO AmiGO |
| Name: | increased amount |
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| Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
| Definition: | An amount which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000470] |