| Phenotype: | G1/S transition of mitotic cell cycle decreased rate, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | G1/S transition of mitotic cell cycle |
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| Synonyms: | |
| Definition: | The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. |
| Ontology: | GO: Biological Process [GO:0000082] QuickGO AmiGO |
| Name: | decreased rate |
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| Synonyms: | slow rate |
| Definition: | A rate which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000911] |