hepatic stellate cell proliferation

Term ID

GO:1990922

Synonyms

• hepatic perisinusoidal cell proliferation
• Ito cell proliferation
• perisinusoidal cell proliferation

Definition

The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO