eif4e-cup complex

Term ID

GO:1990500

Synonyms

• eukaryotic translation initiation factor 4E-cup complex

Definition

A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo. 14723848

References

Ontology

GO: Cellular Component    QuickGO    AmiGO