Search Ontology:
GO: Cellular Component
Bfa1-Bub2 complex
- Term ID
- GO:1990334
- Synonyms
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- Definition
- A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation. 16449187
- References
- Ontology
- GO: Cellular Component QuickGO AmiGO
- is part of
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- is a type of
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Phenotype
Phenotype caused by Genes