Search Ontology:
GO: Cellular Component

mitotic checkpoint complex, CDC20-MAD2 subcomplex

Term ID
GO:1990333
Synonyms
  • CDC20-MAD2 complex
Definition
A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20. 15879521
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
Phenotype
Phenotype caused by Genes
Citations
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