transcription-coupled nucleotide-excision repair, DNA damage recognition complex

Term ID

GO:1990250

Synonyms

Definition

A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex. 22331906

References

Ontology

GO: Cellular Component    QuickGO    AmiGO