GATOR1 complex

Term ID

GO:1990130

Synonyms

• IML1 complex
• SEACIT complex

Definition

A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins. (6)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO