maintenance of unfolded protein involved in ERAD pathway

Term ID

GO:1904378

Synonyms

• chaperone holdase activity
• ERAD chaperone-like activity
• holdase activity
• maintenance of unfolded protein during ERAD
• maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation
• maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway
• maintenance of unfolded protein involved in ER-associated degradation pathway

Definition

Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome. 21636303

References

Ontology

GO: Biological Process    QuickGO    AmiGO