piRNA-mediated gene silencing by mRNA destabilization

Term ID

GO:0140991

Synonyms

Definition

A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO