pore-forming activity

Term ID

GO:0140911

Synonyms

• canonical holin activity
• holin activity
• pinholin activity
• pore forming activity

Definition

An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death. (3)

References

• TC:1.C

Ontology

GO: Molecular Function    QuickGO    AmiGO