PAR polarity complex

Term ID

GO:0120157

Synonyms

• apical polarity complex
• BEM1-CDC24-CLA4 complex
• Cdc42p GEF-PAK complex
• PAR3-PAR6-atypical PKC
• PAR3/PAR6/aPKC
• PAR6-PAR3-aPKC complex

Definition

A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. (4)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO