mCRD-mediated mRNA stability complex

Term ID

GO:0106002

Synonyms

• major coding region determinant of instability-mediated mRNA stability complex
• major coding region instability determinant-mediated mRNA stability complex
• major coding region instability determinant-poly(A)-bridging complex
• major coding-region determinant of instability - poly(A) tail-bridging complex
• mCRD-poly(A)-bridging complex

Definition

A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP. 11051545

References

Ontology

GO: Cellular Component    QuickGO    AmiGO