phosphatidylinositol 3-kinase complex, class I

Term ID

GO:0097651

Synonyms

• class I phosphatidylinositol 3-kinase complex
• class I PI3K complex

Definition

A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast. 24587488

References

Ontology

GO: Cellular Component    QuickGO    AmiGO