negative regulation of excitatory postsynaptic potential

Term ID

GO:0090394

Synonyms

• negative regulation of EPSP
• negative regulation of excitatory post-synaptic membrane potential
• reduction of excitatory postsynaptic membrane potential

Definition

Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

References

Ontology

GO: Biological Process    QuickGO    AmiGO