protein activation cascade

Term ID

GO:0072376

Synonyms

protein activation pathway
protein activitory cascade

Definition

A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: protein maturation

protein maturation Show first 5 Terms
has subtype: blood coagulation, common pathway blood coagulation, extrinsic pathway blood coagulation, fibrin clot formation blood coagulation, intrinsic pathway kinin cascade ... Show All 6 Terms

blood coagulation, common pathway blood coagulation, extrinsic pathway blood coagulation, fibrin clot formation blood coagulation, intrinsic pathway kinin cascade Toll receptor ligand protein activation cascade Show first 5 Terms
inverse has_part: complement activation

complement activation Show first 5 Terms
negatively regulated by: negative regulation of protein activation cascade

negative regulation of protein activation cascade Show first 5 Terms
positively regulated by: positive regulation of protein activation cascade

positive regulation of protein activation cascade Show first 5 Terms
regulated by: regulation of protein activation cascade

regulation of protein activation cascade Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations