LUBAC complex

Term ID

GO:0071797

Synonyms

Definition

A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO