phosphatidylserine exposure on apoptotic cell surface

Term ID

GO:0070782

Synonyms

externalization of phosphatidylserine

Definition

A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity. 11536005

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: execution phase of apoptosis

execution phase of apoptosis Show first 5 Terms
is a type of: plasma membrane phospholipid scrambling

plasma membrane phospholipid scrambling Show first 5 Terms
has_part: phospholipid scramblase activity

phospholipid scramblase activity Show first 5 Terms
negatively regulated by: negative regulation of phosphatidylserine exposure on apoptotic cell surface

negative regulation of phosphatidylserine exposure on apoptotic cell surface Show first 5 Terms
positively regulated by: positive regulation of phosphatidylserine exposure on apoptotic cell surface

positive regulation of phosphatidylserine exposure on apoptotic cell surface Show first 5 Terms
regulated by: regulation of phosphatidylserine exposure on apoptotic cell surface

regulation of phosphatidylserine exposure on apoptotic cell surface Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations