EGFR-Shc-Grb2-Sos complex

Term ID

GO:0070621

Synonyms

Definition

A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO