Shc-Grb2-Sos complex

Term ID

GO:0070619

Synonyms

• Shc-Grb2-mSos1 complex, EGF stimulated

Definition

A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO