Search Ontology:
GO: Cellular Component

Shc-Grb2-Sos complex

Term ID
GO:0070619
Synonyms
  • Shc-Grb2-mSos1 complex, EGF stimulated
Definition
A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. (2)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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